Advances in the progression and prognosis biomarkers of chronic kidney disease

Z Yan, G Wang, X Shi - Frontiers in Pharmacology, 2021 - frontiersin.org
Chronic kidney disease (CKD) is one of the increasingly serious public health concerns
worldwide; the global burden of CKD is increasingly due to high morbidity and mortality. At …

Pathological roles and clinical usefulness of periostin in type 2 inflammation and pulmonary fibrosis

J Ono, M Takai, A Kamei, Y Azuma, K Izuhara - Biomolecules, 2021 - mdpi.com
Periostin is known to be a useful biomarker for various diseases. In this article, we focus on
allergic diseases and pulmonary fibrosis, for which we and others are now developing …

Urinary small extracellular vesicles derived CCL21 mRNA as biomarker linked with pathogenesis for diabetic nephropathy

Y Feng, X Zhong, HF Ni, C Wang, TT Tang… - Journal of Translational …, 2021 - Springer
Background Diabetic nephropathy (DN) is a leading cause of renal failure, whereas the
effective and early diagnostic biomarkers are still lacking. Methods Fourteen cytokines and …

LncRNA NEAT2 modulates pyroptosis of renal tubular cells induced by high glucose in diabetic nephropathy (DN) by via miR-206 regulation

AEA El-Lateef, AGA El-Shemi, MS Alhammady… - Biochemical …, 2022 - Springer
Patients suffering from terminal-stage diabetic nephropathy (DN) are commonly diagnosed
with kidney failure. The condition of DN patients gets generally improved by long-chain …

[HTML][HTML] Interleukin 37 (IL-37) reduces high glucose-induced inflammation, oxidative stress, and apoptosis of podocytes by inhibiting the STAT3–cyclophilin a (CypA) …

X Zhang, Y Zhu, Y Zhou, B Fei - Medical Science Monitor …, 2020 - ncbi.nlm.nih.gov
Background Diabetic nephropathy (DN), the formation of albuminuria, is one of the most
important complications seen in diabetic patients. IL-37, an inhibitor of congenital …

Review of early circulating biomolecules associated with diabetes nephropathy–Ideal candidates for early biomarker array test for DN

KY Quan, CG Yap, NK Jahan, N Pillai - Diabetes research and clinical …, 2021 - Elsevier
Background Diabetic nephropathy (DN) is one of the catastrophic complications of type 2
diabetes mellitus (T2DM). 45% of DN patients progressed to End Stage Renal Disease …

Urinary cyclophilin A as an early marker of chronic kidney disease with underlying type 2 diabetes

P Chatchawal, P Tippayawat, T Somdee… - Scientific Reports, 2024 - nature.com
Cyclophilin A (CypA) is a novel renal inflammation biomarker, with levels altered in various
diseases, particularly in patients with diabetes mellitus (DM) and kidney damage. This study …

Novel Biomarkers for the diagnosis of diabetic nephropathy

M Concepción, J Quiroz, J Suarez… - Caspian Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Diabetes mellitus and its complications are a known public health problem nowadays.
Diabetic nephropathy is one of the main complications and the result of multiple …

WT1 and ACE mRNAs of blood extracellular vesicle as biomarkers of diabetic nephropathy

E Hashemi, H Dehghanbanadaki… - Journal of translational …, 2021 - Springer
Background Diabetic nephropathy (DN) has an increasing global prevalence with excessive
health expenditure and burden. Exosomal mRNAs regulate intercellular communications …

Association between uric acid level and incidence of albuminuria in patients with type 2 diabetes mellitus: A 4.5-year cohort study

YJ Lai, YY Chen, PW Ku, LJ Chen, YF Yen - Medicine, 2021 - journals.lww.com
Using animal models and molecular biology researches, hyperuricemia has been shown to
instruct renal arteriolopathy, arterial hypertension, and microvascular injury involving the …