Nano-drug delivery system targeting tumor microenvironment: a prospective strategy for melanoma treatment

M Xu, S Li - Cancer Letters, 2023 - Elsevier
Melanoma, the most aggressive form of cutaneous malignancy arising from melanocytes, is
frequently characterized by metastasis. Despite considerable progress in melanoma …

Research progress on the synthesis and pharmacology of 1, 3, 4-oxadiazole and 1, 2, 4-oxadiazole derivatives: a mini review

JJ Wang, W Sun, WD Jia, M Bian… - Journal of Enzyme …, 2022 - Taylor & Francis
Oxadiazole is a five-membered heterocyclic compound containing two nitrogen atoms and
one oxygen atom. The 1, 3, 4-oxadiazole and 1, 2, 4-oxadiazole have favourable physical …

[HTML][HTML] Heparan Sulfate Modulation Affects Breast Cancer Cell Adhesion and Transmigration across In Vitro Blood–Brain Barrier

Y Li, DB Shteyman, Z Hachem, AA Ulay, J Fan, BM Fu - Cells, 2024 - mdpi.com
The disruption of endothelial heparan sulfate (HS) is an early event in tumor cell metastasis
across vascular barriers, and the reinforcement of endothelial HS reduces tumor cell …

[HTML][HTML] Signal transduction and gene regulation in the endothelium

MV Levesque, T Hla - Cold Spring Harbor perspectives in medicine, 2023 - ncbi.nlm.nih.gov
Extracellular signals act on G-protein-coupled receptors (GPCRs) to regulate homeostasis
and adapt to stress. This involves rapid intracellular post-translational responses and long …