miRNAs as potential game-changers in bone diseases: Future medicinal and clinical Uses

AS Doghish, MS Elballal, O Elazazy… - … -Research and Practice, 2023 - Elsevier
Abstract MicroRNAs (miRNAs), short, highly conserved non-coding RNA, influence gene
expression by sequential mechanisms such as mRNA breakdown or translational …

miRNAs role in glioblastoma pathogenesis and targeted therapy: Signaling pathways interplay

SS Elshaer, AI Abulsoud, D Fathi… - … -Research and Practice, 2023 - Elsevier
High mortality and morbidity rates and variable clinical behavior are hallmarks of
glioblastoma (GBM), the most common and aggressive primary malignant brain tumor …

A spotlight on the interplay of signaling pathways and the role of miRNAs in osteosarcoma pathogenesis and therapeutic resistance

AS Doghish, M Hegazy, A Ismail, HA El-Mahdy… - … -Research and Practice, 2023 - Elsevier
Osteosarcoma (OS) is one of the most common bone cancers that constantly affects
children, teenagers, and young adults. Numerous epigenetic elements, such as miRNAs …

miRNAs driving diagnosis, progression, and drug resistance in multiple myeloma

MA Elkady, AM Yehia, EGE Elsakka… - … -Research and Practice, 2023 - Elsevier
Multiple myeloma (MM) is a tumor of transformed plasma cells. It's the second most common
hematologic cancer after non-Hodgkin lymphoma. MM is a complex disease with many …

miRNAs role in bladder cancer pathogenesis and targeted therapy: signaling pathways interplay–a review

HA El-Mahdy, EGE Elsakka, AA El-Husseiny… - … -Research and Practice, 2023 - Elsevier
Bladder cancer (BC) is the 11th most popular cancer in females and 4th in males. A lot of
efforts have been exerted to improve BC patients' care. Besides, new approaches have …

The interplay of signaling pathways with miRNAs in cholangiocarcinoma pathogenicity and targeted therapy

MB Zaki, AI Abulsoud, SS Elshaer, D Fathi… - … -Research and Practice, 2023 - Elsevier
Cholangiocarcinoma (CCA), the second most frequent liver cancer after hepatocellular
carcinoma, has been rising worldwide in recent epidemiological research. This neoplasia's …

miRNAs as potential game-changers in melanoma: a comprehensive review

GM Abd-Allah, A Ismail, HA El-Mahdy… - … -Research and Practice, 2023 - Elsevier
Melanoma is the sixth most frequent malignancy. It represents 1.7% of all cancer cases
worldwide. Many risk factors are associated with melanoma including ultraviolet radiation …

miRNAs as potential game-changers in renal cell carcinoma: Future clinical and medicinal uses

MS Elballal, AAM Sallam, AE Elesawy… - … -Research and Practice, 2023 - Elsevier
Renal cell carcinoma (RCC) has the highest mortality rate of all genitourinary cancers, and
its prevalence has grown over time. While RCC can be surgically treated and recurrence is …

The role of miRNAs in laryngeal cancer pathogenesis and therapeutic resistance–A focus on signaling pathways interplay

M Hegazy, MA Elkady, AM Yehia, EGE Elsakka… - … -Research and Practice, 2023 - Elsevier
Laryngeal cancer (LC) is the malignancy of the larynx (voice box). The majority of LC are
squamous cell carcinomas. Many risk factors were reported to be associated with LC as …

The interplay of signaling pathways and miRNAs in the pathogenesis and targeted therapy of esophageal cancer

AS Doghish, AA El-Husseiny… - … -Research and Practice, 2023 - Elsevier
Globally, esophageal cancer (EC) is the 6th leading cause of cancer-related deaths and the
second deadliest gastrointestinal cancer. Multiple genetic and epigenetic factors, such as …