From animal poisons and venoms to medicines: achievements, challenges and perspectives in drug discovery
KCF Bordon, CT Cologna, EC Fornari-Baldo… - Frontiers in …, 2020 - frontiersin.org
Animal poisons and venoms are comprised of different classes of molecules displaying wide-
ranging pharmacological activities. This review aims to provide an in-depth view of toxin …
ranging pharmacological activities. This review aims to provide an in-depth view of toxin …
Entomo-venomics: The evolution, biology and biochemistry of insect venoms
The insects are a hyperdiverse class containing more species than all other animal groups
combined—and many employ venom to capture prey, deter predators and micro-organisms …
combined—and many employ venom to capture prey, deter predators and micro-organisms …
Horizontal gene transfer underlies the painful stings of asp caterpillars (Lepidoptera: Megalopygidae)
Larvae of the genus Megalopyge (Lepidoptera: Zygaenoidea: Megalopygidae), known as
asp or puss caterpillars, produce defensive venoms that cause severe pain. Here, we …
asp or puss caterpillars, produce defensive venoms that cause severe pain. Here, we …
Caterpillar venom: A health hazard of the 21st century
A Seldeslachts, S Peigneur, J Tytgat - Biomedicines, 2020 - mdpi.com
Caterpillar envenomation is a global health threat in the 21st century. Every direct or indirect
contact with the urticating hairs of a caterpillar results in clinical manifestations ranging from …
contact with the urticating hairs of a caterpillar results in clinical manifestations ranging from …
Venoms of Lepidoptera: Evolution, Composition, and Molecular Modes of Action
AA Walker - Annual Review of Entomology, 2024 - annualreviews.org
Animal venoms are a focus of research due to the hazards they represent and to their
relationship to evolution and ecology, pharmacology, biodiscovery, and biotechnology …
relationship to evolution and ecology, pharmacology, biodiscovery, and biotechnology …
Venomous caterpillars: From inoculation apparatus to venom composition and envenomation
Envenomation by the larval or pupal stages of moths occurs when the victim presses their
hairs. They penetrate the subcutaneous tissue, releasing toxins such as proteolytic …
hairs. They penetrate the subcutaneous tissue, releasing toxins such as proteolytic …
Lonomia obliqua Envenoming and Innovative Research
MP Alvarez-Flores, RN Gomes, D Trevisan-Silva… - Toxins, 2021 - mdpi.com
As a tribute to Butantan Institute in its 120th anniversary, this review describes some of the
scientific research efforts carried out in the study of Lonomia envenoming in Brazil, a country …
scientific research efforts carried out in the study of Lonomia envenoming in Brazil, a country …
Regulation by gut bacteria of immune response, Bacillus thuringiensis susceptibility and hemolin expression in Plodia interpunctella
Plodia interpunctella (Hübner) is an important stored grain insect pest worldwide, and the
first lepidopteran with reported resistance to Bacillus thuringiensis (Bt) toxins. Since gut …
first lepidopteran with reported resistance to Bacillus thuringiensis (Bt) toxins. Since gut …
Inflammatory progression in patients undergoing extracorporeal membrane oxygenation
Y Yao, H Kang, Y Cheng, X Su… - Current Molecular …, 2024 - benthamdirect.com
Extracorporeal membrane oxygenation (ECMO) is identified as a novel therapeutic strategy
that offers short-term support to the metabolism of the heart and lungs in humans. Recently …
that offers short-term support to the metabolism of the heart and lungs in humans. Recently …
Neuroprotective effect of rL osac on supplement‐deprived mouse cultured cortical neurons involves maintenance of monocarboxylate transporter MCT 2 protein levels
MP Alvarez‐Flores, A Hébert, C Gouelle… - Journal of …, 2019 - Wiley Online Library
Abstract The recombinant Lonomia obliqua Stuart‐factor activator (rL osac) is a recombinant
hemolin which belongs to the immunoglobulin superfamily of cell adhesion molecules. It is …
hemolin which belongs to the immunoglobulin superfamily of cell adhesion molecules. It is …