Obesity II: establishing causal links between chemical exposures and obesity

JJ Heindel, S Howard, K Agay-Shay, JP Arrebola… - Biochemical …, 2022 - Elsevier
Obesity is a multifactorial disease with both genetic and environmental components. The
prevailing view is that obesity results from an imbalance between energy intake and …

Exposure to phthalates and female reproductive health: A literature review

CG Basso, AT de Araújo-Ramos… - Reproductive …, 2022 - Elsevier
Endocrine-disrupting chemicals (EDCs) are exogenous compounds that have been known
for their ability to interfere with the action of hormones and affect endocrine pathways …

[HTML][HTML] Obesogens: a unifying theory for the global rise in obesity

JJ Heindel, RH Lustig, S Howard… - International Journal of …, 2024 - nature.com
Despite varied treatment, mitigation, and prevention efforts, the global prevalence and
severity of obesity continue to worsen. Here we propose a combined model of obesity, a …

Placenta disrupted: endocrine disrupting chemicals and pregnancy

J Gingrich, E Ticiani, A Veiga-Lopez - Trends in Endocrinology & …, 2020 - cell.com
Endocrine disrupting chemicals (EDCs) are chemicals that can interfere with normal
endocrine signals. Human exposure to EDCs is particularly concerning during vulnerable …

Nonalcoholic fatty liver disease in children: unique considerations and challenges

D Goldner, JE Lavine - Gastroenterology, 2020 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is increasing in prevalence in concert with the
global epidemic of obesity and is being diagnosed at increasingly younger ages. The …

[HTML][HTML] Obesity and endocrine-disrupting chemicals

AA Amato, HB Wheeler, B Blumberg - Endocrine connections, 2021 - ec.bioscientifica.com
Obesity is now a worldwide pandemic. The usual explanation given for the prevalence of
obesity is that it results from consumption of a calorie dense diet coupled with physical …

The association between environmental endocrine disruptors and cardiovascular diseases: a systematic review and meta-analysis

X Fu, J Xu, R Zhang, J Yu - Environmental research, 2020 - Elsevier
Background Except for known cardiovascular risk factors, long-term exposure to
environmental endocrine disruptors (EEDs)–a class of exogenous chemicals, or a mixture of …

Association between gestational PFAS exposure and Children's adiposity in a diverse population

MS Bloom, S Commodore, PL Ferguson, B Neelon… - Environmental …, 2022 - Elsevier
Perfluoroalkyl substances (PFAS) are widely distributed suspected obesogens that cross the
placenta. However, few data are available to assess potential fetal effects of PFAS exposure …

[HTML][HTML] Environmental neglect: endocrine disruptors as underappreciated but potentially modifiable diabetes risk factors

RM Sargis, RA Simmons - Diabetologia, 2019 - Springer
Type 2 diabetes prevalence is increasing dramatically across the globe, imposing a
tremendous toll on individuals and healthcare systems. Reversing these trends requires …

[HTML][HTML] Killing two birds with one stone: Pregnancy is a sensitive window for endocrine effects on both the mother and the fetus

I Plante, LM Winn, C Vaillancourt, P Grigorova… - Environmental …, 2022 - Elsevier
Pregnancy is a complex process requiring tremendous physiological changes in the mother
in order to fulfill the needs of the growing fetus, and to give birth, expel the placenta and …