Bioprinting for the biologist

AC Daly, ME Prendergast, AJ Hughes, JA Burdick - Cell, 2021 - cell.com
Building tissues from scratch to explore entirely new cell configurations could revolutionize
fundamental understanding in biology. Bioprinting is an emerging technology to do this …

Patient-derived organoids in precision medicine: drug screening, organoid-on-a-chip and living organoid biobank

Z Zhou, L Cong, X Cong - Frontiers in Oncology, 2021 - frontiersin.org
Organoids are in vitro self-assembling, organ-like, three-dimensional cellular structures that
stably retain key characteristics of the respective organs. Organoids can be generated from …

Bridging bio–nano science and cancer nanomedicine

M Bjornmalm, KJ Thurecht, M Michael, AM Scott… - ACS …, 2017 - ACS Publications
The interface of bio–nano science and cancer medicine is an area experiencing much
progress but also beset with controversy. Core concepts of the field eg, the enhanced …

CMScaller: an R package for consensus molecular subtyping of colorectal cancer pre-clinical models

PW Eide, J Bruun, RA Lothe, A Sveen - Scientific reports, 2017 - nature.com
Colorectal cancers (CRCs) can be divided into four gene expression-based biologically
distinct consensus molecular subtypes (CMS). This classification provides a potential …

Personalized cancer medicine: an organoid approach

HA Es, L Montazeri, AR Aref, M Vosough… - Trends in …, 2018 - cell.com
Personalized cancer therapy applies specific treatments to each patient. Using personalized
tumor models with similar characteristics to the original tumors may result in more accurate …

[HTML][HTML] Mouse models of colorectal cancer: Past, present and future perspectives

F Bürtin, CS Mullins, M Linnebacher - World journal of …, 2020 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the third most common diagnosed malignancy among both
sexes in the United States as well as in the European Union. While the incidence and …

3D cancer models: One step closer to in vitro human studies

N Manduca, E Maccafeo, R De Maria, A Sistigu… - Frontiers in …, 2023 - frontiersin.org
Cancer immunotherapy is the great breakthrough in cancer treatment as it displayed
prolonged progression-free survival over conventional therapies, yet, to date, in only a …

The future of personalized medicine in space: from observations to countermeasures

E Pavez Loriè, S Baatout, A Choukér… - … in bioengineering and …, 2021 - frontiersin.org
The aim of personalized medicine is to detach from a “one-size fits all approach” and
improve patient health by individualization to achieve the best outcomes in disease …

Gut organoids: mini-tissues in culture to study intestinal physiology and disease

M Almeqdadi, MD Mana, J Roper… - American Journal of …, 2019 - journals.physiology.org
In vitro, cell cultures are essential tools in the study of intestinal function and disease. For the
past few decades, monolayer cellular cultures, such as cancer cell lines or immortalized cell …

The development of ovine gastric and intestinal organoids for studying ruminant host-pathogen interactions

D Smith, DRG Price, A Burrells, MN Faber… - Frontiers in cellular …, 2021 - frontiersin.org
Gastrointestinal (GI) infections in sheep have significant implications for animal health,
welfare and productivity, as well as being a source of zoonotic pathogens. Interactions …