The transient receptor potential ankyrin (TRPA) channels are Ca 2+-permeable nonselective
cation channels remarkably conserved through the animal kingdom. Mammals have only …

Objective The pathophysiology of empty nose syndrome (ENS) remains unclear despite
significant research. The pathophysiologic mechanism of ENS was systematically reviewed …

Adequate perception of nasal airflow (ie, nasal patency) is an important consideration for
patients with nasal sinus diseases. The perception of a lack of nasal patency becomes the …

Objectives/Hypothesis Nasal obstruction is the principal symptom that drives patients with
rhinosinus disease to seek medical treatment. However, patient perception of obstruction …

Background Nasal obstruction is a common otolaryngologic complaint, yet the mechanism of
sensing airflow is not commonly understood. The objective of this work was to review current …

Objectives (1) Analyze the relationship between intranasal airflow distribution and subjective
nasal patency in healthy and nasal airway obstruction (NAO) cohorts using computational …

Objective The precise pathogenesis of empty nose syndrome (ENS) remains unclear.
Various factors such as nasal aerodynamics and sensorineural dysfunction have been …

Objectives This computational study aims to (1) use virtual surgery to theoretically
investigate the maximum possible change in nasal aerodynamics after turbinate surgery,(2) …

Objective Allergic rhinitis (AR) and chronic rhinosinusitis with nasal polyps (CRSwNP) are of
high importance in otorhinolaryngology. Some of their symptoms are related to changes in …

Importance Historically, otolaryngologists have focused on nasal resistance to airflow and
minimum airspace cross-sectional area as objective measures of nasal obstruction using …