Sexually reproducing eukaryotes use recombination between homologous chromosomes to
promote chromosome segregation during meiosis. Meiotic recombination is almost …

Simple Summary The experimental/pathological observation of genome chaos (including
massive and large-scale translocations, chromothripsis, and polyploidy cancer cells) …

Studying the similarities and differences in genomic interactions between species provides
fertile grounds for determining the evolutionary dynamics underpinning genome function …

Although sex chromosomes have evolved from autosomes, they often have unusual
regulatory regimes that are sex-and cell-type-specific such as dosage compensation (DC) …

During meiotic prophase I, tightly regulated processes take place, from pairing and synapsis
of homologous chromosomes to recombination, which are essential for the generation of …

Chromosomal fusions represent one of the most common types of chromosomal
rearrangements found in nature. Yet, their role in shaping the genomic landscape of …

Sex-linked inheritance is a stark exception to Mendel's Laws of Heredity. Here we discuss
how the evolution of heteromorphic sex chromosomes (mainly the Y) has been shaped by …

The kangaroo endogenous retrovirus (KERV) was previously reported to have undergone a
rapid copy number increase in the red-necked wallaby; however, the mode of amplification …

In eutherian mammals, hundreds of programmed DNA double-strand breaks (DSBs) are
generated at the onset of meiosis. The DNA damage response is then triggered. Although …

Although sex chromosomes have evolved from autosomes, they often have unusual
regulatory regimes that are sex-and cell-type-specific such as dosage compensation (DC) …