[HTML][HTML] In vivo methods and applications of xenon-129 magnetic resonance

H Marshall, NJ Stewart, HF Chan, M Rao… - Progress in Nuclear …, 2021 - Elsevier
Hyperpolarised gas lung MRI using xenon-129 can provide detailed 3D images of the
ventilated lung airspaces, and can be applied to quantify lung microstructure and detailed …

Quantification of pulmonary functional MRI: state-of-the-art and emerging image processing methods and measurements

M Sharma, PV Wyszkiewicz… - Physics in Medicine …, 2022 - iopscience.iop.org
Pulmonary functional magnetic resonance imaging (PfMRI) provides a way to non-invasively
map and measure the spatial distribution of pulmonary ventilation, perfusion and gas …

Protocols for multi‐site trials using hyperpolarized 129Xe MRI for imaging of ventilation, alveolar‐airspace size, and gas exchange: A position paper from the 129Xe …

PJ Niedbalski, CS Hall, M Castro… - Magnetic resonance …, 2021 - Wiley Online Library
Hyperpolarized (HP) 129Xe MRI uniquely images pulmonary ventilation, gas exchange, and
terminal airway morphology rapidly and safely, providing novel information not possible …

Using hyperpolarized 129Xe gas-exchange MRI to model the regional airspace, membrane, and capillary contributions to diffusing capacity

Z Wang, L Rankine, EA Bier… - Journal of Applied …, 2021 - journals.physiology.org
Hyperpolarized 129Xe MRI has emerged as a novel means to evaluate pulmonary function
via 3D mapping of ventilation, interstitial barrier uptake, and RBC transfer. However, the …

Quantitative imaging metrics for the assessment of pulmonary pathophysiology: an official American Thoracic Society and Fleischner Society joint workshop report

CCW Hsia, JHT Bates, B Driehuys, SB Fain… - Annals of the …, 2023 - atsjournals.org
Multiple thoracic imaging modalities have been developed to link structure to function in the
diagnosis and monitoring of lung disease. Volumetric computed tomography (CT) renders …

Large-scale investigation of deep learning approaches for ventilated lung segmentation using multi-nuclear hyperpolarized gas MRI

JR Astley, AM Biancardi, PJC Hughes, H Marshall… - Scientific Reports, 2022 - nature.com
Respiratory diseases are leading causes of mortality and morbidity worldwide. Pulmonary
imaging is an essential component of the diagnosis, treatment planning, monitoring, and …

Comparison of Free‐Breathing 3D Phase‐Resolved Functional Lung (PREFUL) MRI With Dynamic 19F Ventilation MRI in Patients With Obstructive Lung Disease …

F Klimeš, AJ Obert, J Scheller… - Journal of Magnetic …, 2024 - Wiley Online Library
Background Non‐contrast‐enhanced 1H magnetic resonance imaging (MRI) with full lung
coverage shows promise for assessment of regional lung ventilation but a comparison with …

Improving Xenon‐129 lung ventilation image SNR with deep‐learning based image reconstruction

NJ Stewart, J de Arcos, AM Biancardi… - Magnetic …, 2024 - Wiley Online Library
Purpose To evaluate the feasibility and utility of a deep learning (DL)‐based reconstruction
for improving the SNR of hyperpolarized 129Xe lung ventilation MRI. Methods 129Xe lung …

PhysVENeT: a physiologically-informed deep learning-based framework for the synthesis of 3D hyperpolarized gas MRI ventilation

JR Astley, AM Biancardi, H Marshall, LJ Smith… - Scientific Reports, 2023 - nature.com
Functional lung imaging modalities such as hyperpolarized gas MRI ventilation enable
visualization and quantification of regional lung ventilation; however, these techniques …

A Dual‐Channel Deep Learning Approach for Lung Cavity Estimation From Hyperpolarized Gas and Proton MRI

JR Astley, AM Biancardi, H Marshall… - Journal of Magnetic …, 2023 - Wiley Online Library
Background Hyperpolarized gas MRI can quantify regional lung ventilation via biomarkers,
including the ventilation defect percentage (VDP). VDP is computed from segmentations …