Potential factors result in diminished ovarian reserve: A comprehensive review

Q Zhu, Y Li, J Ma, H Ma, X Liang - Journal of Ovarian Research, 2023 - Springer
The ovarian reserve is defined as the quantity of oocytes stored in the ovary or the number of
oocytes that can be recruited. Ovarian reserve can be affected by many factors, including …

Targeting adipokines in polycystic ovary syndrome and related metabolic disorders: from experimental insights to clinical studies

Y Xu, H Zhu, W Li, D Chen, Y Xu, A Xu, D Ye - Pharmacology & …, 2022 - Elsevier
Polycystic ovary syndrome (PCOS) affects approximately 15% of women of reproductive age
worldwide. It is the most prevalent endocrine disorder with marked risks for female infertility …

[HTML][HTML] Decrease in ovarian reserve through the inhibition of SIRT1-mediated oxidative phosphorylation

L Guo, X Liu, H Chen, W Wang, C Gu, B Li - Aging (Albany NY), 2022 - ncbi.nlm.nih.gov
Objective: To establish an oxidative stress-induced model of premature ovarian insufficiency
(POI) and to explore the effect of SIRT1 and mitochondrial oxidative phosphorylation on the …

Chronic dietary exposure to a glyphosate-based herbicide results in total or partial reversibility of plasma oxidative stress, cecal microbiota abundance and short-chain …

M Fréville, A Estienne, C Ramé, G Lefort… - Frontiers in …, 2022 - frontiersin.org
Glyphosate-based herbicides (GBHs) are massively used in agriculture. However, few
studies have investigated the effects of glyphosate-based herbicides on avian species …

AdipoRon and other adiponectin receptor agonists as potential candidates in cancer treatments

E Nigro, A Daniele, A Salzillo, A Ragone… - International Journal of …, 2021 - mdpi.com
The high mortality rate together with an ever-growing number of annual cases have defined
neoplastic disorders as “the real 21st-century disease”. Its dubious distinction also results …

Adipose tissue and ovarian aging: Potential mechanism and protective strategies

M Wu, Y Huang, Q Zhu, X Zhu, L Xue, J Xiong… - Ageing Research …, 2022 - Elsevier
Ovarian aging occurs approximately 10 years prior to the natural age-associated functional
decline of other organ systems. With the increase of life expectancy worldwide, ovarian …

[HTML][HTML] Adiponectin inhibits GnRH secretion via activating AMPK and PI3K signaling pathways in chicken hypothalamic neuron cells

X Wu, Y Tao, Y Ren, Z Zhang, Y Zhao, Y Tian, Y Li… - Poultry Science, 2023 - Elsevier
It has been reported that adiponectin (AdipoQ), an adipokine secreted by white adipose
tissue, plays an important role in the control of animal reproduction in addition to its function …

APN expression in serum and corpus luteum: Regulation of luteal steroidogenesis is possibly dependent on the AdipoR2/AMPK pathway in goats

X Pei, H Li, H Yu, W Wang, D Mao - Cells, 2023 - mdpi.com
Adiponectin (APN) is an essential adipokine for a variety of reproductive processes. To
investigate the role of APN in goat corpora lutea (CLs), CLs and sera from different luteal …

Mechanisms and effects of AdipoRon, an adiponectin receptor agonist, on ovarian granulosa cells—a systematic review

LF Laurindo, LF Laurindo, VD Rodrigues… - Naunyn-Schmiedeberg's …, 2024 - Springer
Granulosa cells, crucial components of ovarian follicles, play a fundamental role in follicle
development, hormone production, and overall reproductive health. These cells are integral …

[HTML][HTML] Adiponectin receptor agonist AdipoRon inhibits proliferation and drives glycolytic dependence in non-small-cell lung cancer cells

S Kafeel, A Ragone, A Salzillo, G Palmiero, S Naviglio… - Cancers, 2024 - mdpi.com
Simple Summary NSCLC is one of the most life-threatening forms of oncological diseases.
Although targeted and immunotherapy treatments have improved NSCLC prognosis, the …