Autophagy and apoptosis cascade: which is more prominent in neuronal death?
Autophagy and apoptosis are two crucial self-destructive processes that maintain cellular
homeostasis, which are characterized by their morphology and regulated through signal …
homeostasis, which are characterized by their morphology and regulated through signal …
Exploring the bi‐directional relationship between autophagy and Alzheimer's disease
H Kuang, CY Tan, HZ Tian, LH Liu… - CNS neuroscience & …, 2020 - Wiley Online Library
Alzheimer's disease (AD) is characterized by β‐amyloid (Aβ) deposition and Tau
phosphorylation, in which its pathogenesis has not been cleared so far. The metabolism of …
phosphorylation, in which its pathogenesis has not been cleared so far. The metabolism of …
Autophagy-dependent mechanism of genistein-mediated elimination of behavioral and biochemical defects in the rat model of sporadic Alzheimer's disease
K Pierzynowska, M Podlacha, L Gaffke, I Majkutewicz… - …, 2019 - Elsevier
Alzheimer's disease is one of severe neurological diseases for which no effective treatment
is currently available. The use of genistein (5, 7-dihydroxy-3-(4-hydroxyphenyl)-4H-1 …
is currently available. The use of genistein (5, 7-dihydroxy-3-(4-hydroxyphenyl)-4H-1 …
[HTML][HTML] Trametenolic acid B protects against cerebral ischemia and reperfusion injury through modulation of microRNA-10a and PI3K/Akt/mTOR signaling pathways
J Wang, A Wang, H He, X She, Y He, S Li, L Liu… - Biomedicine & …, 2019 - Elsevier
Trametenolic acid B (TAB) was a lanostane-type triterpenoid isolated from the trametes
lactinea (Berk.) Pat. We have previously reported that extract from trametes lactinea (Berk.) …
lactinea (Berk.) Pat. We have previously reported that extract from trametes lactinea (Berk.) …
Inhibition of inflammation mediated through the tumor necrosis factor α biochemical pathway can lead to favorable outcomes in Alzheimer disease
D Shamim, M Laskowski - Journal of central nervous system …, 2017 - journals.sagepub.com
Tumor necrosis factor α (TNF-α) inhibitors have long been used as disease-modifying
agents in immune disorders. Recently, research has shown a role of chronic …
agents in immune disorders. Recently, research has shown a role of chronic …
[HTML][HTML] Pharmacological modulation of autophagy for Alzheimer's disease therapy: opportunities and obstacles
Alzheimer's disease (AD) is a prevalent and deleterious neurodegenerative disorder
characterized by an irreversible and progressive impairment of cognitive abilities as well as …
characterized by an irreversible and progressive impairment of cognitive abilities as well as …
[HTML][HTML] Assessment of autophagy in neurons and brain tissue
I Benito-Cuesta, H Diez, L Ordoñez, F Wandosell - Cells, 2017 - mdpi.com
Autophagy is a complex process that controls the transport of cytoplasmic components into
lysosomes for degradation. This highly conserved proteolytic system involves dynamic and …
lysosomes for degradation. This highly conserved proteolytic system involves dynamic and …
[HTML][HTML] Streptozotocin-induced Alzheimer's disease investigation by one-dimensional plasmonic grating chip
Recently, there has been significant interest in researching brain insulin resistance as it has
been hypothesized that it may play a role in the progression of Alzheimer's disease …
been hypothesized that it may play a role in the progression of Alzheimer's disease …
Long non-coding RNA BACE1-AS modulates isoflurane-induced neurotoxicity to Alzheimer's disease through sponging miR-214-3p
W He, S Chi, X Jin, J Lu, W Zheng, J Yan… - Neurochemical …, 2020 - Springer
Isoflurane, an anesthetic, can aggravate the progression of Alzheimer's disease (AD). Long
non-coding RNA β-secretase 1 (BACE1)-antisense transcript (BACE1-AS) and miR-214-3p …
non-coding RNA β-secretase 1 (BACE1)-antisense transcript (BACE1-AS) and miR-214-3p …
Knockdown of long non-coding RNA SOX21-AS1 attenuates amyloid-β-induced neuronal damage by sponging miR-107
W Xu, K Li, Q Fan, B Zong, L Han - Bioscience reports, 2020 - portlandpress.com
Background: Alzheimer's disease (AD), which has no effective drugs to delay or prevent its
progression, is a multifactorial complex neurodegenerative disease. Long non-coding RNA …
progression, is a multifactorial complex neurodegenerative disease. Long non-coding RNA …