Contribution of semen to early embryo development: fertilization and beyond

M Vallet-Buisan, R Mecca, C Jones… - Human …, 2023 - academic.oup.com
BACKGROUND It has long been thought that the factors affecting embryo and foetal
development were exclusively maternally derived; hence, if issues regarding fertility and …

[HTML][HTML] The renaissance of male infertility management in the golden age of andrology

AE Calogero, R Cannarella, A Agarwal… - The world journal of …, 2023 - ncbi.nlm.nih.gov
Infertility affects nearly 186 million people worldwide and the male partner is the cause in
about half of the cases. Meta-regression data indicate an unexplained decline in sperm …

[HTML][HTML] The evolution of centriole degradation in mouse sperm

S Khanal, A Jaiswal, R Chowdanayaka… - Nature …, 2024 - nature.com
Centrioles are subcellular organelles found at the cilia base with an evolutionarily
conserved structure and a shock absorber-like function. In sperm, centrioles are found at the …

[HTML][HTML] Centrosome formation in the bovine early embryo

R Uzbekov, GN Singina, EN Shedova, C Banliat… - Cells, 2023 - mdpi.com
Centrosome formation during early development in mice and rats occurs due to the
appearance of centrioles de novo. In contrast, in humans and other non-rodent mammals …

Revisiting the mystery of centrioles at the beginning of mammalian embryogenesis

T Avidor-Reiss, R Uzbekov - Journal of Assisted Reproduction and …, 2023 - Springer
The prevailing assumption has been that the human spermatozoon provides only one
centriole to the zygote: the proximal centriole, with a canonical, cylinder-like shape. This …

The human sperm basal body is a complex centrosome important for embryo preimplantation development

F Amargant, A Pujol, A Ferrer-Vaquer… - Molecular human …, 2021 - academic.oup.com
The mechanism of conversion of the human sperm basal body to a centrosome after
fertilization, and its role in supporting human early embryogenesis, has not been directly …

[HTML][HTML] The reaction-diffusion basis of animated patterns in eukaryotic flagella

JF Cass, H Bloomfield-Gadêlha - Nature Communications, 2023 - nature.com
The flagellar beat of bull spermatozoa and C. Reinhardtii are modelled by a minimal,
geometrically exact, reaction-diffusion system. Spatio-temporal animated patterns describe …

Basal bodies bend in response to ciliary forces

AD Junker, LG Woodhams, AWJ Soh… - Molecular biology of …, 2022 - Am Soc Cell Biol
Motile cilia beat with an asymmetric waveform consisting of a power stroke that generates a
propulsive force and a recovery stroke that returns the cilium back to the start. Cilia are …

[HTML][HTML] The centrosome–diverse functions in fertilization and development across species

A Aljiboury, H Hehnly - Journal of cell science, 2023 - journals.biologists.com
The centrosome is a non-membrane-bound organelle that is conserved across most animal
cells and serves various functions throughout the cell cycle. In dividing cells, the centrosome …

[HTML][HTML] The centriole's role in miscarriages

T Avidor-Reiss, L Achinger, R Uzbekov - Frontiers in Cell and …, 2022 - frontiersin.org
Centrioles are subcellular organelles essential for normal cell function and development;
they form the cell's centrosome (a major cytoplasmic microtubule organization center) and …