In situ self-assembly—the in situ formation of complex materials via biochemical reactions of
monomers—has enhanced the efficacy of drug delivery for cancer therapy and imaging. So …

Hydrogels mimic the tissue environment because of their hydrophilic and porous network
structures. They are widely investigated in biomedical and biotechnological fields, however …

Polyacrylic acid (PAA) and its derivatives are commonly used as essential matrices in
wound dressings, but their weak wet adhesion restricts the clinical application. To address …

A key challenge for the effective treatment of gastrointestinal diseases including
inflammatory bowel disease is to develop an orally administered drug delivery system …

Immune response and new tissue formation are important aspects of tissue repair. However,
only a single aspect is generally considered in previous biomedical interventions, and the …

The fibrotic encapsulation of implants involves the mechanical activation of myofibroblasts
and of pro-fibrotic transforming growth factor beta 1 (TGF-β1). Here, we show that both …

Cell polarization exists in a variety of tissues to regulate cell behaviors and functions. Space
constraint (spatially limiting cell extension) and adhesion induction (guiding adhesome …

Abstract Magnesium cation (Mg 2+) has been an emerging therapeutic agent for inducing
vascularized bone regeneration. However, the therapeutic effects of current magnesium …

Bacterial infection and delayed healing are two major obstacles in cutaneous wound
management, and developing multifunctional hydrogels with antibacterial and prohealing …

Microbial resistance to current antibiotics therapies is a major cause of implant failure and
adverse clinical outcomes in orthopaedic surgery. Recent developments in advanced …