Mammalian fertilization remains a poorly understood event with the vast majority of studies
done in the mouse model. The purpose of this review is to revise the current knowledge …

Sperm-zona pellucida (ZP) interaction, involving the binding of sperm surface ligands to
complementary carbohydrates of ZP, is the first direct gamete contact event crucial for …

Sperm capacitation is a post-testicular maturation step endowing spermatozoa with
fertilizing capacity within the female reproductive tract, significant for fertility, reproductive …

Persulfidation contributes to a group of redox post-translational modifications (PTMs), which
arise exclusively on the sulfhydryl group of cysteine as a result of hydrogen sulfide (H2S) …

Background and Aims N‐nitroso compounds (NOCs) are among the most potent dietary
carcinogens. N‐nitrosodiethylamine (NDEA), N‐nitrosodimethylamine (NDMA), and N …

The degradation of sperm-borne mitochondria after fertilization is a conserved event. This
process known as post-fertilization sperm mitophagy, ensures exclusively maternal …

Conclusions The test–retest reliability of HVPG is overall excellent. Within‐individual
variance was higher in studies including higher proportions of decompensated patients …

For fully differentiated, long lived cells the maintenance of protein homeostasis
(proteostasis) becomes a crucial determinant of cellular function and viability. Neurons are …

Sperm capacitation is a complex process endowing biological and biochemical changes to
a spermatozoon for a successful encounter with an oocyte. The present study focused on the …

Sperm proteins undergo post-translational modifications, such as phosphorylation,
acetylation, and ubiquitination, which in turn play a key role in determining their fertilizing …