Mechanical considerations for polymeric heart valve development: Biomechanics, materials, design and manufacturing
The native human heart valve leaflet contains a layered microstructure comprising a
hierarchical arrangement of collagen, elastin, proteoglycans and various cell types. Here …
hierarchical arrangement of collagen, elastin, proteoglycans and various cell types. Here …
Clinical impact of computational heart valve models
This paper provides a review of engineering applications and computational methods used
to analyze the dynamics of heart valve closures in healthy and diseased states …
to analyze the dynamics of heart valve closures in healthy and diseased states …
Biologically inspired scaffolds for heart valve tissue engineering via melt electrowriting
Heart valves are characterized to be highly flexible yet tough, and exhibit complex
deformation characteristics such as nonlinearity, anisotropy, and viscoelasticity, which are …
deformation characteristics such as nonlinearity, anisotropy, and viscoelasticity, which are …
Deep autoencoders for physics-constrained data-driven nonlinear materials modeling
Physics-constrained data-driven computing is an emerging computational paradigm that
allows simulation of complex materials directly based on material database and bypass the …
allows simulation of complex materials directly based on material database and bypass the …
Manifold learning based data-driven modeling for soft biological tissues
Data-driven modeling directly utilizes experimental data with machine learning techniques
to predict a material's response without the necessity of using phenomenological constitutive …
to predict a material's response without the necessity of using phenomenological constitutive …
A detailed mechanical and microstructural analysis of ovine tricuspid valve leaflets
The tricuspid valve ensures unidirectional blood flow from the right atrium to the right
ventricle. The three tricuspid leaflets operate within a dynamic stress environment of shear …
ventricle. The three tricuspid leaflets operate within a dynamic stress environment of shear …
Parameterization, geometric modeling, and isogeometric analysis of tricuspid valves
EL Johnson, DW Laurence, F Xu, CE Crisp… - Computer methods in …, 2021 - Elsevier
Approximately 1.6 million patients in the United States are affected by tricuspid valve
regurgitation, which occurs when the tricuspid valve does not close properly to prevent …
regurgitation, which occurs when the tricuspid valve does not close properly to prevent …
A physics-guided neural operator learning approach to model biological tissues from digital image correlation measurements
We present a data-driven workflow to biological tissue modeling, which aims to predict the
displacement field based on digital image correlation (DIC) measurements under unseen …
displacement field based on digital image correlation (DIC) measurements under unseen …
An investigation of regional variations in the biaxial mechanical properties and stress relaxation behaviors of porcine atrioventricular heart valve leaflets
The facilitation of proper blood flow through the heart depends on proper function of heart
valve components, and alterations to any component can lead to heart disease or failure …
valve components, and alterations to any component can lead to heart disease or failure …
Mechanics of the tricuspid valve—From clinical diagnosis/treatment, in-vivo and in-vitro investigations, to patient-specific biomechanical modeling
Proper tricuspid valve (TV) function is essential to unidirectional blood flow through the right
side of the heart. Alterations to the tricuspid valvular components, such as the TV annulus …
side of the heart. Alterations to the tricuspid valvular components, such as the TV annulus …