Microtubules and their role in cellular stress in cancer
AL Parker, M Kavallaris, JA McCarroll - Frontiers in oncology, 2014 - frontiersin.org
Microtubules are highly dynamic structures, which consist of α-and β-tubulin heterodimers,
and are involved in cell movement, intracellular trafficking, and mitosis. In the context of …
and are involved in cell movement, intracellular trafficking, and mitosis. In the context of …
Biological actions of the Hsp90-binding immunophilins FKBP51 and FKBP52
NR Zgajnar, SA De Leo, CM Lotufo, AG Erlejman… - Biomolecules, 2019 - mdpi.com
Immunophilins are a family of proteins whose signature domain is the peptidylprolyl-
isomerase domain. High molecular weight immunophilins are characterized by the …
isomerase domain. High molecular weight immunophilins are characterized by the …
[HTML][HTML] The nuclear receptor field: a historical overview and future challenges
GI Mazaira, NR Zgajnar, CM Lotufo… - Nuclear receptor …, 2018 - ncbi.nlm.nih.gov
In this article we summarize the birth of the field of nuclear receptors, the discovery of
untransformed and transformed isoforms of ligand-binding macromolecules, the discovery of …
untransformed and transformed isoforms of ligand-binding macromolecules, the discovery of …
HSP90AB1: Helping the good and the bad
M Haase, G Fitze - Gene, 2016 - Elsevier
HSP90AB1 (heat shock protein 90 kDA alpha, class B, member 1), also known as
HSP90beta, is a member of the large family of HSPs which function as molecular …
HSP90beta, is a member of the large family of HSPs which function as molecular …
Multi-omic profiling reveals the ataxia protein sacsin is required for integrin trafficking and synaptic organization
LEL Romano, WY Aw, KM Hixson, TV Novoselova… - Cell Reports, 2022 - cell.com
Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is a childhood-onset
cerebellar ataxia caused by mutations in SACS, which encodes the protein sacsin. Cellular …
cerebellar ataxia caused by mutations in SACS, which encodes the protein sacsin. Cellular …
Regulatory role of the 90-kDa-heat-shock protein (Hsp90) and associated factors on gene expression
AG Erlejman, M Lagadari, J Toneatto… - … et Biophysica Acta (BBA …, 2014 - Elsevier
The term molecular chaperone was first used to describe the ability of nucleoplasmin to
prevent the aggregation of histones with DNA during the assembly of nucleosomes …
prevent the aggregation of histones with DNA during the assembly of nucleosomes …
[HTML][HTML] Novel therapeutic strategies for ischemic heart disease
AJ Perricone, RS Vander Heide - Pharmacological research, 2014 - Elsevier
Despite significant advances in the physician's ability to initiate myocardial reperfusion and
salvage heart tissue, ischemic heart disease remains one of the leading causes of death in …
salvage heart tissue, ischemic heart disease remains one of the leading causes of death in …
Regulation of the glucocorticoid response to stress‐related disorders by the Hsp90‐binding immunophilin FKBP51
NM Galigniana, LT Ballmer, J Toneatto… - Journal of …, 2012 - Wiley Online Library
J. Neurochem.(2012) 122, 4–18. Abstract Immunophilin is the collective name given to a
family of proteins that bind immunosuppressive drugs: Some immunophilins are Hsp90 …
family of proteins that bind immunosuppressive drugs: Some immunophilins are Hsp90 …
Behcet Disease serum is immunoreactive to neurofilament medium which share common epitopes to bacterial HSP-65, a putative trigger
S Lule, AI Colpak, B Balci-Peynircioglu… - Journal of …, 2017 - Elsevier
Autoimmune and dysimmune inflammatory mechanisms on a genetically susceptible
background are implicated in the etiology of Behçet's Disease (BD). Heat-shock protein-65 …
background are implicated in the etiology of Behçet's Disease (BD). Heat-shock protein-65 …
Regulation of epithelial and endothelial barriers by molecular chaperones
S Lechuga, A Marino-Melendez, NG Naydenov, A Zafar… - Cells, 2024 - mdpi.com
The integrity and permeability of epithelial and endothelial barriers depend on the formation
of tight junctions, adherens junctions, and a junction-associated cytoskeleton. The …
of tight junctions, adherens junctions, and a junction-associated cytoskeleton. The …