Carbon-based glyco-nanoplatforms: towards the next generation of glycan-based multivalent probes
J Ramos-Soriano, M Ghirardello… - Chemical Society Reviews, 2022 - pubs.rsc.org
Cell surface carbohydrates mediate a wide range of carbohydrate–protein interactions key
to healthy and disease mechanisms. Many of such interactions are multivalent in nature and …
to healthy and disease mechanisms. Many of such interactions are multivalent in nature and …
Synthesis and biological application of glyco-and peptide derivatives of fullerene C60
L Tanzi, M Terreni, Y Zhang - European Journal of Medicinal Chemistry, 2022 - Elsevier
Fullerenes have attracted considerable attention for their possible use in human therapy.
Pure C 60 is soluble only in some organic solvents, but this could be overcome by chemical …
Pure C 60 is soluble only in some organic solvents, but this could be overcome by chemical …
Multivalent glycosylated nanostructures to inhibit Ebola virus infection
The infection of humans by lethal pathogens such as Ebola and other related viruses has
not been properly addressed so far. In this context, a relevant question arises: What can …
not been properly addressed so far. In this context, a relevant question arises: What can …
Glycodendritic structures as DC-SIGN binders to inhibit viral infections
J Ramos-Soriano, J Rojo - Chemical Communications, 2021 - pubs.rsc.org
DC-SIGN, a lectin discovered two decades ago, plays a relevant role in innate immunity.
Since its discovery, it has turned out to be a target for developing antiviral drugs based on …
Since its discovery, it has turned out to be a target for developing antiviral drugs based on …
Antiviral activity of self-assembled glycodendro [60] fullerene monoadducts
A series of amphiphilic glycodendro [60] fullerene monoadducts were efficiently synthesized
using the CuAAC “click chemistry” approach. These glycodendrofullerenes can self …
using the CuAAC “click chemistry” approach. These glycodendrofullerenes can self …
Multifaceted glycodendrimers with programmable bioactivity through convergent, divergent, and accelerated approaches using polyfunctional cyclotriphosphazenes
L Abbassi, YM Chabre, N Kottari, AA Arnold… - Polymer …, 2015 - pubs.rsc.org
We report the sequential construction of a set of multivalent structures using
cyclotriphosphazene (CTP) units, which were extensively used as primary or secondary …
cyclotriphosphazene (CTP) units, which were extensively used as primary or secondary …
Multivalent Tryptophan‐and Tyrosine‐Containing [60] Fullerene Hexa‐Adducts as Dual HIV and Enterovirus A71 Entry Inhibitors
M Ruiz‐Santaquiteria, BM Illescas… - … A European Journal, 2021 - Wiley Online Library
Unprecedented 3D hexa‐adducts of [60] fullerene peripherally decorated with twelve
tryptophan (Trp) or tyrosine (Tyr) residues have been synthesized. Studies on the antiviral …
tryptophan (Trp) or tyrosine (Tyr) residues have been synthesized. Studies on the antiviral …
Construction of giant glycosidase inhibitors from iminosugar-substituted fullerene macromonomers
TMN Trinh, M Holler, JP Schneider… - Journal of Materials …, 2017 - pubs.rsc.org
An ultra-fast synthetic procedure based on grafting of twelve fullerene macromonomers onto
a fullerene hexa-adduct core was used for the preparation of a giant molecule with 120 …
a fullerene hexa-adduct core was used for the preparation of a giant molecule with 120 …
C60‐based Multivalent Glycoporphyrins Inhibit SARS‐CoV‐2 Specific Interaction with the DC‐SIGN Transmembrane Receptor
J Patino‐Alonso, J Cabrera‐González, J Merino… - Small, 2024 - Wiley Online Library
Since WHO has declared the COVID‐19 outbreak a global pandemic, nearly seven million
deaths have been reported. This efficient spread of Severe Acute Respiratory Syndrome …
deaths have been reported. This efficient spread of Severe Acute Respiratory Syndrome …
Multivalent cationic dendrofullerenes for gene transfer: Synthesis and DNA complexation
BM Illescas, A Pérez-Sánchez, A Mallo… - Journal of Materials …, 2020 - pubs.rsc.org
Non-viral nucleic acid vectors able to display high transfection efficiencies with low toxicity
and overcoming the multiple biological barriers are needed to further develop the clinical …
and overcoming the multiple biological barriers are needed to further develop the clinical …