[HTML][HTML] Life in the human stomach: persistence strategies of the bacterial pathogen Helicobacter pylori
NR Salama, ML Hartung, A Müller - Nature Reviews Microbiology, 2013 - nature.com
The bacterial pathogen Helicobacter pylori has co-evolved with humans and colonizes
approximately 50% of the human population, but only causes overt gastric disease in a …
approximately 50% of the human population, but only causes overt gastric disease in a …
The hydrodynamics of swimming microorganisms
Cell motility in viscous fluids is ubiquitous and affects many biological processes, including
reproduction, infection and the marine life ecosystem. Here we review the biophysical and …
reproduction, infection and the marine life ecosystem. Here we review the biophysical and …
[HTML][HTML] In vivo activation of pH-responsive oxidase-like graphitic nanozymes for selective killing of Helicobacter pylori
L Zhang, L Zhang, H Deng, H Li, W Tang… - Nature …, 2021 - nature.com
Helicobacter pylori infection is a major etiological factor in gastric diseases. However,
clinical antibiotic therapy for H. pylori is limited by continuously decreased therapeutic …
clinical antibiotic therapy for H. pylori is limited by continuously decreased therapeutic …
Helicobacter pylori adhesin HopQ engages in a virulence-enhancing interaction with human CEACAMs
A Javaheri, T Kruse, K Moonens, R Mejías-Luque… - Nature …, 2016 - nature.com
Helicobacter pylori specifically colonizes the human gastric epithelium and is the major
causative agent for ulcer disease and gastric cancer development. Here, we identify …
causative agent for ulcer disease and gastric cancer development. Here, we identify …
Activation of the Raf-MEK-ERK pathway is required for neutrophil extracellular trap formation
The signaling mechanisms leading to the formation of neutrophil extracellular traps (NETs),
relevant in infections, sepsis and autoimmune diseases, are poorly understood. Neutrophils …
relevant in infections, sepsis and autoimmune diseases, are poorly understood. Neutrophils …
[图书][B] The organic chemistry of drug design and drug action
RB Silverman, MW Holladay - 2014 - books.google.com
The Organic Chemistry of Drug Design and Drug Action, Third Edition, represents a unique
approach to medicinal chemistry based on physical organic chemical principles and …
approach to medicinal chemistry based on physical organic chemical principles and …
Microswimming in viscoelastic fluids
The locomotion of microorganisms and spermatozoa in complex viscoelastic fluids is of
critical importance in many biological processes such as fertilization, infection, and biofilm …
critical importance in many biological processes such as fertilization, infection, and biofilm …
Helicobacter pylori moves through mucus by reducing mucin viscoelasticity
The ulcer-causing gastric pathogen Helicobacter pylori is the only bacterium known to
colonize the harsh acidic environment of the human stomach. H. pylori survives in acidic …
colonize the harsh acidic environment of the human stomach. H. pylori survives in acidic …
Nonredox nickel enzymes
MJ Maroney, S Ciurli - Chemical reviews, 2014 - ACS Publications
The importance of nickel enzymes, where nickel serves as an essential cofactor, in Archaea,
bacteria, plants, and primitive eukaryotes, is well documented. 1 Despite the fact that no …
bacteria, plants, and primitive eukaryotes, is well documented. 1 Despite the fact that no …
Persistent bacterial infections: the interface of the pathogen and the host immune system
DM Monack, A Mueller, S Falkow - Nature Reviews Microbiology, 2004 - nature.com
Persistent bacterial infections involving Mycobacterium tuberculosis, Salmonella enterica
serovar Typhi (S. typhi) and Helicobacter pylori pose significant public-health problems …
serovar Typhi (S. typhi) and Helicobacter pylori pose significant public-health problems …