[HTML][HTML] Life in the human stomach: persistence strategies of the bacterial pathogen Helicobacter pylori

NR Salama, ML Hartung, A Müller - Nature Reviews Microbiology, 2013 - nature.com
The bacterial pathogen Helicobacter pylori has co-evolved with humans and colonizes
approximately 50% of the human population, but only causes overt gastric disease in a …

The hydrodynamics of swimming microorganisms

E Lauga, TR Powers - Reports on progress in physics, 2009 - iopscience.iop.org
Cell motility in viscous fluids is ubiquitous and affects many biological processes, including
reproduction, infection and the marine life ecosystem. Here we review the biophysical and …

[HTML][HTML] In vivo activation of pH-responsive oxidase-like graphitic nanozymes for selective killing of Helicobacter pylori

L Zhang, L Zhang, H Deng, H Li, W Tang… - Nature …, 2021 - nature.com
Helicobacter pylori infection is a major etiological factor in gastric diseases. However,
clinical antibiotic therapy for H. pylori is limited by continuously decreased therapeutic …

Helicobacter pylori adhesin HopQ engages in a virulence-enhancing interaction with human CEACAMs

A Javaheri, T Kruse, K Moonens, R Mejías-Luque… - Nature …, 2016 - nature.com
Helicobacter pylori specifically colonizes the human gastric epithelium and is the major
causative agent for ulcer disease and gastric cancer development. Here, we identify …

Activation of the Raf-MEK-ERK pathway is required for neutrophil extracellular trap formation

A Hakkim, TA Fuchs, NE Martinez, S Hess… - Nature chemical …, 2011 - nature.com
The signaling mechanisms leading to the formation of neutrophil extracellular traps (NETs),
relevant in infections, sepsis and autoimmune diseases, are poorly understood. Neutrophils …

[图书][B] The organic chemistry of drug design and drug action

RB Silverman, MW Holladay - 2014 - books.google.com
The Organic Chemistry of Drug Design and Drug Action, Third Edition, represents a unique
approach to medicinal chemistry based on physical organic chemical principles and …

Microswimming in viscoelastic fluids

G Li, E Lauga, AM Ardekani - Journal of Non-Newtonian Fluid Mechanics, 2021 - Elsevier
The locomotion of microorganisms and spermatozoa in complex viscoelastic fluids is of
critical importance in many biological processes such as fertilization, infection, and biofilm …

Helicobacter pylori moves through mucus by reducing mucin viscoelasticity

JP Celli, BS Turner, NH Afdhal… - Proceedings of the …, 2009 - National Acad Sciences
The ulcer-causing gastric pathogen Helicobacter pylori is the only bacterium known to
colonize the harsh acidic environment of the human stomach. H. pylori survives in acidic …

Nonredox nickel enzymes

MJ Maroney, S Ciurli - Chemical reviews, 2014 - ACS Publications
The importance of nickel enzymes, where nickel serves as an essential cofactor, in Archaea,
bacteria, plants, and primitive eukaryotes, is well documented. 1 Despite the fact that no …

Persistent bacterial infections: the interface of the pathogen and the host immune system

DM Monack, A Mueller, S Falkow - Nature Reviews Microbiology, 2004 - nature.com
Persistent bacterial infections involving Mycobacterium tuberculosis, Salmonella enterica
serovar Typhi (S. typhi) and Helicobacter pylori pose significant public-health problems …