Over the past decade, great progress has been made in understanding the complexity of
adipose tissue biology and its role in metabolism. This includes new insights into the …

Adipose tissue is a complex endocrine organ, with a role in obesity and cancer. Adipose
tissue is generally linked to excessive body fat, and it is well known that the female breast is …

The mammary gland (MG) is an exocrine gland present in female mammals responsible for
the production and secretion of milk during the process of lactation. It is mainly composed by …

Breast cancer prevention is daunting, yet not an unsurmountable goal. Mammary stem and
progenitors have been proposed as the cells‐of‐origin in breast cancer. Here, we present …

The mammary gland is a unique tissue and the defining feature of the class Mammalia. It is a
late-evolving epidermal appendage that has the primary function of providing nutrition for …

Cancer metabolism adapts the metabolic network of its tissue of origin. However, breast
cancer is not a disease of a single origin. Multiple epithelial populations serve as the culprit …

The biologic basis of genetic ancestry-dependent variability in disease incidence and
outcome is just beginning to be explored. We recently reported enrichment of a population of …

In adults, hepatocytes are mainly replenished from the existing progenitor pools of
hepatocytes and cholangiocytes during chronic liver injury. However, it is unclear whether …

Cellular plasticity is a transformation of a terminally differentiated cell into another cell type,
which has been long known to occur in disease and regeneration. However, white …

White adipocytes in the mammary gland stroma comprise the majority of the mammary gland
mass. White adipocytes regulate numerous hormonal and metabolic processes and exhibit …