[HTML][HTML] Clinical quantitative cardiac imaging for the assessment of myocardial ischaemia

M Dewey, M Siebes, M Kachelrieß, KF Kofoed… - Nature Reviews …, 2020 - nature.com
Cardiac imaging has a pivotal role in the prevention, diagnosis and treatment of ischaemic
heart disease. SPECT is most commonly used for clinical myocardial perfusion imaging …

Quantitative clinical nuclear cardiology, Part 1: Established applications

EV Garcia, P Slomka, JB Moody, G Germano… - Journal of Nuclear …, 2020 - Elsevier
Single photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI)
has attained widespread clinical acceptance as a standard of care for patients with known or …

AI-defined cardiac anatomy improves risk stratification of hybrid perfusion imaging

RJH Miller, A Shanbhag, A Killekar, M Lemley… - JACC: Cardiovascular …, 2024 - Elsevier
Background Computed tomography attenuation correction (CTAC) improves perfusion
quantification of hybrid myocardial perfusion imaging by correcting for attenuation artifacts …

Mitigating bias in deep learning for diagnosis of coronary artery disease from myocardial perfusion SPECT images

RJH Miller, A Singh, Y Otaki, BK Tamarappoo… - European journal of …, 2023 - Springer
Purpose Artificial intelligence (AI) has high diagnostic accuracy for coronary artery disease
(CAD) from myocardial perfusion imaging (MPI). However, when trained using high-risk …

Quality metrics for single-photon emission computed tomography myocardial perfusion imaging: an ASNC information statement

FG Hage, AJ Einstein, K Ananthasubramaniam… - Journal of Nuclear …, 2023 - Elsevier
The central mission of the American Society of Nuclear Cardiology (ASNC) is to improve
cardiovascular outcomes through image-guided patient management. The most commonly …

Automated quantitative analysis of CZT SPECT stratifies cardiovascular risk in the obese population: Analysis of the REFINE SPECT registry

E Klein, RJH Miller, T Sharir, AJ Einstein… - Journal of Nuclear …, 2022 - Elsevier
Background Obese patients constitute a substantial proportion of patients referred for
SPECT myocardial perfusion imaging (MPI), presenting a challenge of increased soft tissue …

External validation of the CRAX2MACE model

W Hijazi, W Leslie, N Filipchuk, R Choo, S Wilton… - Journal of Nuclear …, 2023 - Elsevier
Background Single-photon emission computed tomography (SPECT) myocardial perfusion
is frequently used to predict risk of major adverse cardiovascular events (MACE). We …

Quantitation of poststress change in ventricular morphology improves risk stratification

RJH Miller, T Sharir, Y Otaki, H Gransar… - Journal of Nuclear …, 2021 - Soc Nuclear Med
Shape index and eccentricity index are measures of left ventricular morphology. Although
both measures can be quantified with any stress imaging modality, they are not routinely …

Current status of myocardial perfusion imaging with new SPECT/CT cameras

E Piekarski, A Manrique, F Rouzet… - Seminars in Nuclear …, 2020 - Elsevier
Myocardial perfusion imaging (MPI) with Single-Photon Emission Computed Tomography
(SPECT) has a major role in the management of coronary artery disease. Recent …

The Relationship Between Quantitative Ischemia, Early Revascularization, and Major Adverse Cardiovascular Events: A Multicenter Study

RJH Miller, B Bednarski, Y Cui, V Calsavara, K Patel… - JACC: Advances, 2025 - jacc.org
Background Observational data have suggested that patients with moderate to severe
ischemia benefit from revascularization. However, this was not confirmed in a large …