Novel inhibitor-based therapies for thyroid cancer—An update

M Ratajczak, D Gaweł, M Godlewska - International journal of molecular …, 2021 - mdpi.com
Thyroid cancers (TCs) are the most common tumors of the endocrine system and a constant
rise in the number of TC cases has been observed for the past few decades. TCs are one of …

Redifferentiation of differentiated thyroid cancer: clinical insights from a narrative review of literature

D Van Nostrand, I Veytsman, K Kulkarni, L Heimlich… - Thyroid, 2023 - liebertpub.com
Background: Patients who have metastatic differentiated thyroid cancer (mDTC) frequently
have negative diagnostic and/or post-therapy radioiodine scans. As a result, 131I therapy is …

[PDF][PDF] SNMMI procedure standard/EANM practice guideline for nuclear medicine evaluation and therapy of differentiated thyroid cancer: abbreviated version

AM Avram, L Giovanella, B Greenspan, SA Lawson… - 2022 - Soc Nuclear Med
Editor's note: SNMMI and the European Association of Nuclear Medicine periodically define
new standards/guidelines for nuclear medicine practice to help advance the science of …

State of the art in the current management and future directions of targeted therapy for differentiated thyroid cancer

H Silaghi, V Lozovanu, CE Georgescu, C Pop… - International Journal of …, 2022 - mdpi.com
Two-thirds of differentiated thyroid cancer (DTC) patients with distant metastases would be
classified as radioactive iodine-refractory (RAIR-DTC), evolving into a poor outcome. Recent …

Curcumin induces mitophagy by promoting mitochondrial succinate dehydrogenase activity and sensitizes human papillary thyroid carcinoma BCPAP cells to …

L Zhang, L Qiu, S Xu, X Cheng, J Wu, Y Wang, W Gao… - Toxicology in Vitro, 2023 - Elsevier
Thyroid cancer is one of the most common endocrine malignancies. Differentiated thyroid
cancer (DTC) treatment is based on the ability of thyroid follicular cells to accumulate …

A randomized, phase III study of lenvatinib in Chinese patients with radioiodine-refractory differentiated thyroid cancer

X Zheng, Z Xu, Q Ji, M Ge, F Shi, J Qin, F Wang… - Clinical Cancer …, 2021 - AACR
Purpose: Lenvatinib has shown efficacy in treating radioiodine-refractory differentiated
thyroid cancer (RR-DTC) in the multinational phase III SELECT study; however, it has not …

Curcumin induces autophagic cell death in human thyroid cancer cells

L Zhang, S Xu, X Cheng, J Wu, L Wu, Y Wang, X Wang… - Toxicology in Vitro, 2022 - Elsevier
Curcumin, a polyphenolic compound, is a well-known anticancer agent, although its poor
bioavailability remains a big concern. Recent studies suggest that autophagy-targeted …

Comparison of the Therapeutic Effects of [211At]NaAt and [131I]NaI in an NIS-Expressing Thyroid Cancer Mouse Model

T Watabe, Y Liu, K Kaneda-Nakashima, T Sato… - International Journal of …, 2022 - mdpi.com
Astatine (211At) is an alpha-emitter with a better treatment efficacy against differentiated
thyroid cancer compared with iodine (131I), a conventional beta-emitter. However, its …

Poorly differentiated thyroid carcinoma: a clinician's perspective

J Tong, M Ruan, Y Jin, H Fu, L Cheng… - European Thyroid …, 2022 - etj.bioscientifica.com
Poorly differentiated thyroid carcinoma (PDTC) is a rare thyroid carcinoma originating from
follicular epithelial cells. No explicit consensus can be achieved to date due to sparse …

Advancements in the treatment of differentiated thyroid cancer

LA Stewart, JH Kuo - Therapeutic Advances in …, 2021 - journals.sagepub.com
Derived from follicular epithelial cells, differentiated thyroid cancer (DTC) accounts for the
majority of thyroid malignancies. The threefold increase in DTC incidence over the last three …