Designing tailored thiosemicarbazones with bespoke properties: The styrene moiety imparts potent activity, inhibits heme center oxidation, and results in a novel “ …

M Dharmasivam, B Kaya, T Wijesinghe… - Journal of Medicinal …, 2023 - ACS Publications
A novel, potent, and selective antitumor agent, namely (E)-3-phenyl-1-(2-pyridinyl)-2-propen-
1-one 4, 4-dimethyl-3-thiosemicarbazone (PPP44mT), and its analogues were synthesized …

Synthesis, Characterization, and Biological Properties of the Copper(II) Complexes with Novel Ligand: N-[4-({2-[1-(pyridin-2-yl)ethylidene]hydrazinecarbothioyl}amino …

R Rusnac, O Garbuz, Y Chumakov, V Tsapkov… - Inorganics, 2023 - mdpi.com
For the first time, a thiosemicarbazone-type ligand containing a paracetamol structural unit
was synthesized. Five new coordination compounds based on copper (II) salts:[Cu (L) …

[PDF][PDF] Biological activity of copper (II) complex (2-((2-(prop-2-en-1-ylcarbamothioyl) hydrazinylidene) methyl) phenolato)-chloro-copper (II) monohydrate

O Garbuz, V Graur, I Graur, N Railean… - J. Cancer Sci. Clin …, 2024 - academia.edu
Abstract The ligand 2-(2-hydroxybenzylidene)-N-(prop-2-en-1-yl) hydrazinecarbothioamide
(H2L) and its copper (II) coordination compound (2-((2-(prop-2-en-1-ylcarbamothioyl) …