[HTML][HTML] The ACE2/angiotensin-(1–7)/MAS axis of the renin-angiotensin system: focus on angiotensin-(1–7)

RAS Santos, WO Sampaio, AC Alzamora… - Physiological …, 2017 - journals.physiology.org
The renin-angiotensin system (RAS) is a key player in the control of the cardiovascular
system and hydroelectrolyte balance, with an influence on organs and functions throughout …

Role of oxidative stress as key regulator of muscle wasting during cachexia

J Ábrigo, AA Elorza, CA Riedel, C Vilos… - Oxidative medicine …, 2018 - Wiley Online Library
Skeletal muscle atrophy is a pathological condition mainly characterized by a loss of
muscular mass and the contractile capacity of the skeletal muscle as a consequence of …

Muscle memory and a new cellular model for muscle atrophy and hypertrophy

K Gundersen - Journal of Experimental Biology, 2016 - journals.biologists.com
Memory is a process in which information is encoded, stored, and retrieved. For vertebrates,
the modern view has been that it occurs only in the brain. This review describes a cellular …

ACE2, angiotensin 1-7 and skeletal muscle: review in the era of COVID-19

K Yamamoto, H Takeshita, H Rakugi - Clinical Science, 2020 - portlandpress.com
Abstract Angiotensin converting enzyme-2 (ACE2) is a multifunctional transmembrane
protein recently recognised as the entry receptor of the virus causing COVID-19. In the renin …

Renin‐angiotensin system: an old player with novel functions in skeletal muscle

C Cabello‐Verrugio, MG Morales… - Medicinal research …, 2015 - Wiley Online Library
Skeletal muscle is a tissue that shows the most plasticity in the body; it can change in
response to physiological and pathological stimuli. Among the diseases that affect skeletal …

Cholic acid and deoxycholic acid induce skeletal muscle atrophy through a mechanism dependent on TGR5 receptor

J Abrigo, F Gonzalez, F Aguirre, F Tacchi… - Journal of Cellular …, 2021 - Wiley Online Library
Skeletal muscle atrophy is characterized by the degradation of myofibrillar proteins, such as
myosin heavy chain or troponin. An increase in the expression of two muscle‐specific E3 …

High fat diet‐induced skeletal muscle wasting is decreased by mesenchymal stem cells administration: implications on oxidative stress, ubiquitin proteasome pathway …

J Abrigo, JC Rivera, J Aravena… - Oxidative medicine …, 2016 - Wiley Online Library
Obesity can lead to skeletal muscle atrophy, a pathological condition characterized by the
loss of strength and muscle mass. A feature of muscle atrophy is a decrease of myofibrillar …

Significance of angiotensin 1–7 coupling with MAS1 receptor and other GPCRs to the renin‐angiotensin system: IUPHAR Review 22

SS Karnik, KD Singh, K Tirupula… - British journal of …, 2017 - Wiley Online Library
Angiotensins are a group of hormonal peptides and include angiotensin II and angiotensin 1–
7 produced by the renin angiotensin system. The biology, pharmacology and biochemistry of …

Modulation of the renin–angiotensin system in white adipose tissue and skeletal muscle: focus on exercise training

EDC Frantz, E Prodel, ID Braz, IG Giori… - Clinical …, 2018 - portlandpress.com
Overactivation of the renin–angiotensin (Ang) system (RAS) increases the classical arm
(Ang-converting enzyme (ACE)/Ang II/Ang type 1 receptor (AT1R)) to the detriment of the …

[HTML][HTML] Ubiquitin ligases at the heart of skeletal muscle atrophy control

D Peris-Moreno, L Cussonneau, L Combaret, C Polge… - Molecules, 2021 - mdpi.com
Skeletal muscle loss is a detrimental side-effect of numerous chronic diseases that
dramatically increases mortality and morbidity. The alteration of protein homeostasis is …