Peripheral and central immune cells are critical for fighting disease, but they can also play a
pivotal role in the onset and/or progression of a variety of neurological conditions that affect …

Role of calcium ion (Ca2+) in the functioning of neurons from their naive state to mature
state is of vital importance. It controls functions such as neuronal functioning, neuronal ATP …

The dorsal root ganglion (DRG) is a highly vulnerable site in diabetic neuropathy. Under
diabetic conditions, the DRG is subjected to tissue ischemia or lower ambient oxygen …

Recently, telocytes (TCs) were described as a new cell type in the interstitial space of many
organs, including myometrium. TCs are cells with very long, distinctive extensions named …

Background Previous studies have shown that increased excitability of capsaicin-sensitive
DRG neurons and thermal hyperalgesia in rats with short-term (2–4 weeks) streptozotocin …

Peripheral neuropathy is one of the main complications of diabetes. The pathogenesis of
this affectation is not completely understood. Several studies refer to hyperglycemia as the …

Previous studies have shown that diabetic peripheral neuropathy affects both unmyelinated
and myelinated afferents, similar to those evoking the exercise pressor reflex. However, the …

Increasing incidence of metabolic disturbances has become a severe public healthcare
problem. Ion channels and receptors in the paraventricular nucleus (PVN) of the …

Acid‐sensing ion channels (ASIC s) are proton‐gated channels involved in multiple
biological functions such as: pain modulation, mechanosensation, neurotransmission, and …

Ion channels are integral membrane proteins that orchestrate the passage of ions across the
cell membrane and thus regulate various key physiological processes of the living system …