The objective of this Review is to describe the safety and efficacy of adipose stem/stromal
cells (ASC) and stromal vascular fraction (SVF) in treating common diseases and the next …

Background: Adult mesenchymal stem cells (MSCs) were first isolated from bone marrow by
Friedenstein in 1976. These cells were clonogenic, non-haematopoietic, and able to …

Background: Following successful preclinical studies, stem cell therapy is emerging as a
candidate for the treatment of articular cartilage lesions. Because stem cell therapy for …

Background The increasing push to commercialize university research has emerged as a
significant science policy challenge. While the socio-economic benefits of increased and …

Background Chondral lesions of the knee represent a challenge for the orthopaedic
surgeon. Several treatments have been proposed with variable success rate. Recently, new …

The meniscal tear treatment paradigm traditionally begins with conservative measures such
as physical therapy and referral for operative management for persistent or mechanical …

Penetrating keratoplasty was the only therapeutic choice for the treatment of corneal
endothelial decompensation until the introduction of evolutional endothelial keratoplasties …

Hundreds of businesses and clinics in the United States are engaged in direct-to-consumer
marketing of unproven and unlicensed stem cell–based interventions. This essay provides …

Purpose The management of knee pain secondary to meniscal tears with osteoarthritis is
limited by the poor inherent healing potential of the meniscus. Previous studies have …

The application of regenerative strategies to musculoskeletal ailments offers extraordinary
promise to transform management of the conditions of numerous patients. The use of cell …