Pattern recognition receptors (PRRs) are a class of receptors that can directly recognize the
specific molecular structures on the surface of pathogens, apoptotic host cells, and damaged …

Aspergillus fumigatus is a saprotrophic fungus; its primary habitat is the soil. In its ecological
niche, the fungus has learned how to adapt and proliferate in hostile environments. This …

Fungal infections are a global concern and the evolution of intrinsic resistance to current
antifungals presents an alarming problem. For Cryptococcus neoformans, a human fungal …

Although antibiotics have been indispensable in the advancement of modern medicine,
there are downsides to their use. Growing resistance to broad-spectrum antibiotics is …

The special features that liposome-based drug delivery systems have shown are useful in
solving biological and pharmacodynamic hurdles. Features such as biodegradability and …

The bacterial pathogen Mycobacterium tuberculosis binds to the C-type lectin DC-SIGN
(dendritic cell–specific intercellular adhesion molecule 3-grabbing nonintegrin) on dendritic …

Lectins are proteins found in all domains of life with a plethora of biological functions,
especially in the infection process, immune response, and inflammation. Targeting these …

Combatting the ever-increasing threat from invasive fungal pathogens faces numerous
fundamental challenges, including constant human exposure to large reservoirs of species …

This review attempts to frame the issues around antifungal drug resistance. From its
epidemiology, mechanisms, measurements, and clinical significance, invasive fungal …

Active research of metal-containing compounds and enzymes as effective antifungal agents
is currently being conducted due to the growing antifungal resistance problem. Metals are …