Elastin-like polypeptides for biomedical applications

AK Varanko, JC Su, A Chilkoti - Annual review of biomedical …, 2020 - annualreviews.org
Elastin-like polypeptides (ELPs) are stimulus-responsive biopolymers derived from human
elastin. Their unique properties—including lower critical solution temperature phase …

Applications of elastin-like polypeptides in drug delivery

SR MacEwan, A Chilkoti - Journal of Controlled Release, 2014 - Elsevier
Elastin-like polypeptides (ELPs) are biopolymers inspired by human elastin. Their lower
critical solution temperature phase transition behavior and biocompatibility make them …

Protein-based nanoparticles for drug delivery purposes

AL Martínez-López, C Pangua, C Reboredo… - International journal of …, 2020 - Elsevier
Proteins represent a group of biopolymers with interesting properties to be employed as raw
materials in the preparation of nanoparticles for drug delivery purposes. Due to the inherent …

Putting the spotlight back on plant suspension cultures

RB Santos, R Abranches, R Fischer, M Sack… - Frontiers in plant …, 2016 - frontiersin.org
Plant cell suspension cultures have several advantages that make them suitable for the
production of recombinant proteins. They can be cultivated under aseptic conditions using …

Development of systems for the production of plant-derived biopharmaceuticals

KB Moon, JS Park, YI Park, IJ Song, HJ Lee, HS Cho… - Plants, 2019 - mdpi.com
Over the last several decades, plants have been developed as a platform for the production
of useful recombinant proteins due to a number of advantages, including rapid production …

Maximizing the production of recombinant proteins in plants: from transcription to protein stability

Z Feng, X Li, B Fan, C Zhu, Z Chen - International Journal of Molecular …, 2022 - mdpi.com
The production of therapeutic and industrial recombinant proteins in plants has advantages
over established bacterial and mammalian systems in terms of cost, scalability, growth …

New trends and affinity tag designs for recombinant protein purification

DW Wood - Current opinion in structural biology, 2014 - Elsevier
Highlights•Compares and contrasts new affinity methods to dominant conventional
methods.•Explains how the popular His tag, despite its age, still dominates this …

Protein based therapeutic delivery agents: Contemporary developments and challenges

L Yin, C Yuvienco, JK Montclare - Biomaterials, 2017 - Elsevier
As unique biopolymers, proteins can be employed for therapeutic delivery. They bear
important features such as bioavailability, biocompatibility, and biodegradability with low …

Elastin‐like polypeptides: A strategic fusion partner for biologics

A Yeboah, RI Cohen, C Rabolli… - Biotechnology and …, 2016 - Wiley Online Library
Elastin‐like peptides (ELPs) are derivatives of tropoelastin with a unique property that allows
them to stay soluble below a certain critical temperature but reversibly form aggregates …

[HTML][HTML] On the way to commercializing plant cell culture platform for biopharmaceuticals: present status and prospect

J Xu, N Zhang - Pharmaceutical bioprocessing, 2014 - ncbi.nlm.nih.gov
Plant cell culture is emerging as an alternative bioproduction system for recombinant
pharmaceuticals. Growing plant cells in vitro under controlled environmental conditions …