Biodegradable calcium phosphate nanoparticles for cancer therapy
R Khalifehzadeh, H Arami - Advances in colloid and interface science, 2020 - Elsevier
Calcium phosphate is the inorganic mineral of hard tissues such as bone and teeth. Due to
their similarities to the natural bone, calcium phosphates are highly biocompatible and …
their similarities to the natural bone, calcium phosphates are highly biocompatible and …
Recent advances in the design, development, and targeting mechanisms of polymeric micelles for delivery of siRNA in cancer therapy
Small interfering RNA (siRNA) is a relatively novel nucleic acid-based therapy to treat
diseases such as cancer. Nevertheless, substantial obstacles to its clinical applications have …
diseases such as cancer. Nevertheless, substantial obstacles to its clinical applications have …
[HTML][HTML] Control of stem cell fate by engineering their micro and nanoenvironment
Stem cells are capable of long-term self-renewal and differentiation into specialised cell
types, making them an ideal candidate for a cell source for regenerative medicine. The …
types, making them an ideal candidate for a cell source for regenerative medicine. The …
Melittin derived peptides for nanoparticle based siRNA transfection
KK Hou, H Pan, GM Lanza, SA Wickline - Biomaterials, 2013 - Elsevier
Traditional transfection agents including cationic lipids and polymers have high efficiency
but cause cytotoxicity. While cell penetrating peptide based transfection agents exhibit …
but cause cytotoxicity. While cell penetrating peptide based transfection agents exhibit …
Directing stem cell fate by controlled RNA interference
WWY Yau, P Rujitanaroj, L Lam, SY Chew - Biomaterials, 2012 - Elsevier
Directing stem cell fate remains a major area of interest and also a hurdle to many,
particularly in the field of regenerative medicine. Unfortunately, conventional methods of …
particularly in the field of regenerative medicine. Unfortunately, conventional methods of …
An inhalable β2-adrenoceptor ligand-directed guanidinylated chitosan carrier for targeted delivery of siRNA to lung
SiRNA-based strategies appear to be an exciting new approach for the treatment of
respiratory diseases. To extrapolate siRNA-mediated interventions from bench to bedside in …
respiratory diseases. To extrapolate siRNA-mediated interventions from bench to bedside in …
Silica-coated calcium phosphate nanoparticles for gene silencing of NF-κB p65 by siRNA and their impact on cellular players of inflammation
N Białas, EK Müller, M Epple, I Hilger - Biomaterials, 2021 - Elsevier
The transcription factor NF-κB and its signaling cascade both play key roles in all
inflammatory processes. The most critical member of the NF-κB transcription factor family is …
inflammatory processes. The most critical member of the NF-κB transcription factor family is …
Anti-tumor effects in mice induced by survivin-targeted siRNA delivered through polysaccharide nanoparticles
Recently, survivin has been attracting great attention because it plays an important role in
inhibiting the apoptosis process of tumor cells. Down-regulating the expression of survivin …
inhibiting the apoptosis process of tumor cells. Down-regulating the expression of survivin …
Effect of binding affinity for siRNA on the in vivo antitumor efficacy of polyplexes
L Han, C Tang, C Yin - Biomaterials, 2013 - Elsevier
To elucidate the effect of binding affinity for siRNA on the in vivo antitumor efficacy of
polyplexes, five kinds of galactose modified trimethyl chitosan-cysteine (GTC) conjugate …
polyplexes, five kinds of galactose modified trimethyl chitosan-cysteine (GTC) conjugate …
[HTML][HTML] RNAi nanomaterials targeting immune cells as an anti-tumor therapy: the missing link in cancer treatment?
siRNA delivery targeting tumor cells and cancer-associated immune cells has been gaining
momentum in the last few years. A combinatorial approach for silencing crucial factors …
momentum in the last few years. A combinatorial approach for silencing crucial factors …