Diabetic gastrointestinal motility disorders and the role of enteric nervous system: current status and future directions

SS Yarandi, S Srinivasan - Neurogastroenterology & Motility, 2014 - Wiley Online Library
Background Gastrointestinal manifestations of diabetes are common and a source of
significant discomfort and disability. Diabetes affects almost every part of gastrointestinal …

Diabetes and the enteric nervous system

B Chandrasekharan… - Neurogastroenterology & …, 2007 - Wiley Online Library
Diabetes is associated with several changes in gastrointestinal (GI) motility and associated
symptoms such as nausea, bloating, abdominal pain, diarrhoea and constipation. The …

Interactions between the microbiota and enteric nervous system during gut-brain disorders

S Fried, E Wemelle, PD Cani, C Knauf - Neuropharmacology, 2021 - Elsevier
For the last 20 years, researchers have focused their intention on the impact of gut
microbiota in healthy and pathological conditions. This year (2021), more than 25,000 …

Targeting mitochondrial biogenesis for preventing and treating insulin resistance in diabetes and obesity: Hope from natural mitochondrial nutrients

J Liu, W Shen, B Zhao, Y Wang, K Wertz… - Advanced drug delivery …, 2009 - Elsevier
Insulin resistance is an important feature of type 2 diabetes and obesity. The underlying
mechanisms of insulin resistance are still unclear and may involve pathological changes in …

Diabetic enteropathy: from molecule to mechanism‐based treatment

T Meldgaard, SS Olesen, AD Farmer… - Journal of diabetes …, 2018 - Wiley Online Library
The incidence of the micro‐and macrovascular complications of diabetes is rising, mirroring
the increase in the worldwide prevalence. Arguably, the most common microvascular …

[PDF][PDF] T. gondii infection acquired during pregnancy and/or after birth may be responsible for development of both type 1 and 2 diabetes mellitus

J Prandota - J Diabetes Metab, 2013 - researchgate.net
Recently, it was suggested that maternal T and potentially B cells transferred during
pregnancy and/or the breast milk feeding and their encounter with the antigen in mesenteric …

CD44 fucosylation on bone marrow-derived mesenchymal stem cells enhances homing and promotes enteric nervous system remodeling in diabetic mice

H Shi, C Jiang, H Yao, Y Zhang, Q Zhang, X Hou… - Cell & Bioscience, 2021 - Springer
Background Diabetes can cause extensive enteric nervous system (ENS) injuries and
gastrointestinal motility disorder. In developing possible treatments, researchers have …

Immunohistochemical study of vasoactive intestinal peptide (VIP) enteric neurons in diabetic rats supplemented with L-glutamine

EPB Alves, AMP Alves, RVF Pereira… - Nutritional …, 2010 - Taylor & Francis
The purpose of this work was to study the area of the varicosities of nerve fibers of myenteric
neurons immunoreactive to vasoactive intestinal peptide (VIP-IR) and of the cell bodies of …

Protective effects of R‐alpha‐lipoic acid and acetyl‐L‐carnitine in MIN6 and isolated rat islet cells chronically exposed to oleic acid

W Shen, K Liu, C Tian, L Yang, X Li… - Journal of Cellular …, 2008 - Wiley Online Library
Mitochondrial dysfunction due to oxidative stress and concomitant impaired β‐cell function
may play a key role in type 2 diabetes. Preventing and/or ameliorating oxidative …

Quantification of nitrergic neurons in the myenteric plexus of gastric antrum and ileum of healthy and diabetic dogs

F Giancola, F Fracassi, A Gallucci… - Autonomic …, 2016 - Elsevier
Diabetes mellitus (DM) determines a wide array of severe clinical complications including
gastrointestinal motility disorders. The present study investigates the effects of spontaneous …