The current landscape of NKT cell immunotherapy and the hills ahead
Simple Summary Natural killer T (NKT) cells are a subset of lipid-reactive T cells that
enhance anti-tumor immunity. While preclinical studies have shown NKT cell …
enhance anti-tumor immunity. While preclinical studies have shown NKT cell …
Poly (lactic acid)-based particulate systems are promising tools for immune modulation
Abstract Poly (lactic acid)(PLA) is one of the most successful and versatile polymers
explored for controlled delivery of bioactive molecules. Its attractive properties of …
explored for controlled delivery of bioactive molecules. Its attractive properties of …
NKT cell networks in the regulation of tumor immunity
CD1d-restricted natural killer T (NKT) cells lie at the interface between the innate and
adaptive immune systems and are important mediators of immune responses and tumor …
adaptive immune systems and are important mediators of immune responses and tumor …
Nanoparticle mediated cancer immunotherapy
The versatility and nanoscale size have helped nanoparticles (NPs) improve the efficacy of
conventional cancer immunotherapy and opened up exciting approaches to combat cancer …
conventional cancer immunotherapy and opened up exciting approaches to combat cancer …
Synergistic induction of adaptive antitumor immunity by codelivery of antigen with α-galactosylceramide on exosomes
U Gehrmann, S Hiltbrunner, AM Georgoudaki… - Cancer research, 2013 - AACR
Exosomes and the invariant NKT (iNKT) immune cell ligand α-galactosylceramide (αGC)
may offer novel tools for cancer immunotherapy. In this study, we investigated whether …
may offer novel tools for cancer immunotherapy. In this study, we investigated whether …
Application of nanotechnologies for improved immune response against infectious diseases in the developing world
M Look, A Bandyopadhyay, JS Blum… - Advanced drug delivery …, 2010 - Elsevier
There is an urgent need for new strategies to combat infectious diseases in developing
countries. Many pathogens have evolved to elude immunity and this has limited the utility of …
countries. Many pathogens have evolved to elude immunity and this has limited the utility of …
cGAMP-adjuvanted multivalent influenza mRNA vaccines induce broadly protective immunity through cutaneous vaccination in mice
Increasing preclinical and clinical results have demonstrated that mRNA vaccines efficiently
prevent infectious diseases and are safe in animal models and humans. In this study, we …
prevent infectious diseases and are safe in animal models and humans. In this study, we …
Nanotechnology-based manipulation of dendritic cells for enhanced immunotherapy strategies
R Klippstein, D Pozo - Nanomedicine: Nanotechnology, Biology and …, 2010 - Elsevier
Dendritic cells (DCs) are potent antigen-presenting cells capable of initiating a primary
immune response and possess the ability to activate T cells and stimulate the growth and …
immune response and possess the ability to activate T cells and stimulate the growth and …
Robust IgG responses to nanograms of antigen using a biomimetic lipid-coated particle vaccine
New subunit vaccine formulations with increased potency are of interest to improve immune
responses against poorly immunogenic antigens, to avoid vaccine shortages in pandemic …
responses against poorly immunogenic antigens, to avoid vaccine shortages in pandemic …
[HTML][HTML] Selection of adjuvants for enhanced vaccine potency
W Wang, M Singh - World Journal of Vaccines, 2011 - scirp.org
The advent of mass vaccination has saved millions of human lives and revolutionized the
quality of life. Vaccination is currently one of the most cost effective ways of managing …
quality of life. Vaccination is currently one of the most cost effective ways of managing …