Hydroamination, the addition of an N–H bond across a C–C multiple bond, is a reaction with
a great synthetic potential. Important advances have been made in the last decades …

The past decade has witnessed some remarkable advances in our appreciation of the
structural and reaction chemistry of the heavier alkaline earth (Ae= Mg, Ca, Sr, Ba) elements …

Azetidines are prominent structural scaffolds in bioactive molecules, medicinal chemistry,
and ligand design for transition metals. However, state-of-the-art methods cannot be applied …

The intermolecular hydroamination of unactivated alkenes with simple dialkyl amines
remains an unsolved problem in organic synthesis. We report a catalytic protocol for efficient …

Enantiomerically pure chiral amines are valuable building blocks for the synthesis of
pharmaceutical drugs and agrochemicals. Indeed it is estimated that currently 40% of …

Organometallic chemistry is generally considered the key to homogeneous catalysis, which,
although a century old, is still today a very dynamic discipline. 1 The past decade has seen …

Here we present the first example of a single-site main group catalyst stabilized by a metal–
organic framework (MOF) for organic transformations. The straightforward metalation of the …

Herein we report a metal-free method for the direct anti-Markovnikov hydroamination of
unsaturated amines. Irradiation of the amine substrates with visible light in the presence of …

While olefin amination with aminium radical cations is a classical method for C–N bond
formation, catalytic variants that utilize simple 2° amine precursors remain largely …

Utilization of main-group metals as alternatives to transition metals in homogeneous
catalysis has become a hot research area in recent years. However, their application in …