How to improve awareness, treatment, and control of hypertension in Africa, and how to reduce its consequences: a call to action from the World Hypertension League

G Parati, DT Lackland, NRC Campbell… - …, 2022 - Am Heart Assoc
Hypertension is the leading preventable risk factor for cardiovascular diseases and disability
globally. In low-and middle-income countries hypertension has a major social impact …

Metabolic syndrome: sex-related cardiovascular risk and therapeutic approach

F Santilli, D DArdes… - Current medicinal …, 2017 - ingentaconnect.com
Background: The metabolic syndrome (MetS) is a cluster of risk factors for the development
of cardiovascular diseases (CVD) and type 2 diabetes (T2DM). According to several meta …

Risk of myocardial infarction among people living with HIV: an updated systematic review and meta-analysis

O Eyawo, G Brockman, CH Goldsmith, MW Hull… - BMJ open, 2019 - bmjopen.bmj.com
Objective Cardiovascular disease (CVD) is one of the leading non-AIDS-defining causes of
death among HIV-positive (HIV+) individuals. However, the evidence surrounding specific …

Insulin resistance in HIV-patients: causes and consequences

MN Pedro, GZ Rocha, D Guadagnini… - Frontiers in …, 2018 - frontiersin.org
Here we review how immune activation and insulin resistance contribute to the metabolic
alterations observed in HIV-infected patients, and how these alterations increase the risk of …

Association of Antiretroviral Therapy with Platelet Function and Systemic Inflammatory Response in People Living with HIV: A Cross-Sectional Study

K Akinosoglou, M Kolosaka, G Schinas, AL Delastic… - Microorganisms, 2023 - mdpi.com
People living with HIV (PLWHIV) present an increased risk of adverse cardiovascular
events. We aimed to assess whether antiretroviral therapy (ART) pharmacologically …

Drug-microbiota interactions: an emerging priority for precision medicine

Q Zhao, Y Chen, W Huang, H Zhou… - Signal Transduction and …, 2023 - nature.com
Individual variability in drug response (IVDR) can be a major cause of adverse drug
reactions (ADRs) and prolonged therapy, resulting in a substantial health and economic …

HIV and its relationship to insulin resistance and lipid abnormalities

LR Non, GV Escota, WG Powderly - Translational Research, 2017 - Elsevier
Antiretroviral therapy has revolutionized the care of people with human immunodeficiency
virus (HIV) by reducing morbidity and mortality from acquired immunodeficiency syndrome …

Body mass index trends and its impact of under and overweight on outcome among PLHIV on antiretroviral treatment in rural Tanzania: A prospective cohort study

AV Kalinjuma, H Hussey, GJ Mollel, E Letang… - Plos one, 2023 - journals.plos.org
Introduction Increased body weight is an important risk factor for cardiovascular disease and
is increasingly reported as a health problem in people living with HIV (PLHIV). There is …

Prevalence and factors associated with hypertension among people living with HIV/AIDS on antiretroviral therapy in Uganda

G Lubega, B Mayanja, J Lutaakome, A Abaasa… - Pan African Medical …, 2021 - ajol.info
Introduction: antiretroviral therapy (ART) has improved survival of People Living with HIV
(PLWH); however, this has resulted in an increasingly high prevalence of non …

HIV-associated cardiovascular disease: importance of platelet activation and cardiac fibrosis in the setting of specific antiretroviral therapies

J Laurence, S Elhadad, J Ahamed - Open Heart, 2018 - openheart.bmj.com
HIV infection is a risk factor for cardiovascular disease (CVD). This risk is accentuated by
certain combination antiretroviral therapies (cARTs), independent of their effects on lipid …