[HTML][HTML] Pathophysiological mechanisms and therapeutic approaches in obstructive sleep apnea syndrome

R Lv, X Liu, Y Zhang, N Dong, X Wang, Y He… - Signal transduction and …, 2023 - nature.com
Obstructive sleep apnea syndrome (OSAS) is a common breathing disorder in sleep in
which the airways narrow or collapse during sleep, causing obstructive sleep apnea. The …

Evaluation and management of adults with obstructive sleep apnea syndrome

JJ Lee, KM Sundar - Lung, 2021 - Springer
Obstructive sleep apnea syndrome (OSAS) is a common and underdiagnosed medical
condition characterized by recurrent sleep-dependent pauses and reductions in airflow …

Phenotypes in obstructive sleep apnea: a definition, examples and evolution of approaches

AV Zinchuk, MJ Gentry, J Concato, HK Yaggi - Sleep medicine reviews, 2017 - Elsevier
Obstructive sleep apnea (OSA) is a complex and heterogeneous disorder and the apnea
hypopnea index alone can not capture the diverse spectrum of the condition. Enhanced …

Upper-airway collapsibility and loop gain predict the response to oral appliance therapy in patients with obstructive sleep apnea

BA Edwards, C Andara, S Landry… - American journal of …, 2016 - atsjournals.org
Rationale: Oral appliances (OAs) are commonly used as an alternative treatment to
continuous positive airway pressure for patients with obstructive sleep apnea (OSA) …

[HTML][HTML] Mandibular advancement device design: a systematic review on outcomes in obstructive sleep apnea treatment

JAMU Venema, BRAM Rosenmöller, N De Vries… - Sleep medicine …, 2021 - Elsevier
Summary Obstructive Sleep Apnea (OSA) is often treated with Mandibular Advancement
Devices (MADs). It is unclear whether particular design features are superior to others in …

Polysomnographic endotyping to select patients with obstructive sleep apnea for oral appliances

AA Bamagoos, PA Cistulli, K Sutherland… - Annals of the …, 2019 - atsjournals.org
Rationale: Oral appliance therapy is efficacious in many patients with obstructive sleep
apnea (OSA), but prediction of treatment outcome is challenging. Small, detailed …

[HTML][HTML] Comparison of the phenotypic characteristics between responders and non-responders to obstructive sleep apnea treatment using mandibular advancement …

S Camanes-Gonzalvo, C Bellot-Arcis… - Sleep Medicine …, 2022 - Elsevier
Mandibular advancement device (MAD) therapy is the most commonly used second-line
treatment for obstructive sleep apnea (OSA), but MAD may be ineffective in a subgroup of …

Phenotypes of responders to mandibular advancement device therapy in obstructive sleep apnea patients: A systematic review and meta-analysis

H Chen, DJ Eckert, PF van der Stelt, J Guo, S Ge… - Sleep medicine …, 2020 - Elsevier
Mandibular advancement device (MAD) therapy is the most commonly used non-continuous
positive airway pressure (CPAP) treatment for obstructive sleep apnea (OSA). Although OSA …

[PDF][PDF] Efficacy versus effectiveness in the treatment of obstructive sleep apnea: CPAP and oral appliances

K Sutherland, CL Phillips, PA Cistulli - J Dent Sleep Med, 2015 - mysleepdevice.com
Obstructive sleep apnea (OSA) is a chronic disorder and effective long-term treatment is
necessary to prevent associated health risks. Standard treatment remains continuous …

Mandibular advancement device treatment efficacy is associated with polysomnographic endotypes

S Op de Beeck, M Dieltjens, A Azarbarzin… - Annals of the …, 2021 - atsjournals.org
Rationale: Mandibular advancement device (MAD) treatment efficacy varies among patients
with obstructive sleep apnea. Objectives: The current study aims to explain underlying …