Background & aims The incidence of inflammatory bowel disease (IBD) is increasing
internationally, particularly in nations with historically low rates. Previous reports of the …

Inflammatory bowel disease (IBD) is a global disease; its evolution can be stratified into four
epidemiological stages: Emergence, Acceleration in Incidence, Compounding Prevalence …

Background & Aims Inflammatory bowel diseases (IBDs) exist worldwide, with high
prevalence in North America. IBD is complex and costly, and its increasing prevalence …

Background: The contemporary management of ambulatory ulcerative colitis (UC) continues
to be challenging with∼ 20% of children needing a colectomy within childhood years. We …

Background Stricturing and penetrating complications account for substantial morbidity and
health-care costs in paediatric and adult onset Crohn's disease. Validated models to predict …

AIM To perform a comprehensive review and provide an up-to-date synopsis of the
incidence and trends of inflammatory bowel disease (IBD). METHODS We systematically …

Patients with a diverse spectrum of rare genetic disorders can present with inflammatory
bowel disease (monogenic IBD). Patients with these disorders often develop symptoms …

Objectives: The incidence of pediatric-onset inflammatory bowel disease (IBD) is increasing
worldwide. We used population-based health administrative data to determine national …

Antibiotic use is increasing worldwide. However, the use of antibiotics is clearly associated
with changes in gut microbiome composition and function, and perturbations have been …

Very early onset inflammatory bowel disease (VEO-IBD) is defined as IBD presenting before
6 years of age. When compared with IBD diagnosed in older children, VEO-IBD has some …