Chemodynamic therapy via fenton and fenton‐like nanomaterials: strategies and recent advances

C Jia, Y Guo, FG Wu - Small, 2022 - Wiley Online Library
Chemodynamic therapy (CDT), a novel cancer therapeutic strategy defined as the treatment
using Fenton or Fenton‐like reaction to produce• OH in the tumor region, was first proposed …

Manipulating intratumoral fenton chemistry for enhanced chemodynamic and chemodynamic‐synergized multimodal therapy

Y Zhou, S Fan, L Feng, X Huang, X Chen - Advanced Materials, 2021 - Wiley Online Library
Chemodynamic therapy (CDT) uses the tumor microenvironment‐assisted intratumoral
Fenton reaction for generating highly toxic hydroxyl free radicals (• OH) to achieve selective …

Engineering nanomedicine for glutathione depletion-augmented cancer therapy

Y Xiong, C Xiao, Z Li, X Yang - Chemical Society Reviews, 2021 - pubs.rsc.org
Glutathione (GSH), the main redox buffer, has long been recognized as a pivotal modulator
of tumor initiation, progression and metastasis. It is also implicated in the resistance of …

Biomedicine meets Fenton chemistry

Z Tang, P Zhao, H Wang, Y Liu, W Bu - Chemical reviews, 2021 - ACS Publications
Since the first connection between Fenton chemistry and biomedicine, numerous studies
have been presented in this field. Comprehensive presentation of the guidance from Fenton …

Enhanced chemodynamic therapy by Cu–Fe peroxide nanoparticles: tumor microenvironment-mediated synergistic Fenton reaction

S Koo, OK Park, J Kim, SI Han, TY Yoo, N Lee… - ACS …, 2022 - ACS Publications
An urgent need in chemodynamic therapy (CDT) is to achieve high Fenton catalytic
efficiency at small doses of CDT agents. However, simple general promotion of the Fenton …

Recent progress of chemodynamic therapy-induced combination cancer therapy

X Wang, X Zhong, Z Liu, L Cheng - Nano Today, 2020 - Elsevier
Chemodynamic therapy (CDT) is an emerging cancer treatment strategy that uses CDT
agents to convert hydrogen peroxide (H 2 O 2) into the hydroxyl radical (radical dotOH), the …

[HTML][HTML] Recent progress in nanomedicine for enhanced cancer chemotherapy

G Wei, Y Wang, G Yang, Y Wang, R Ju - Theranostics, 2021 - ncbi.nlm.nih.gov
As one of the most important cancer treatment strategies, conventional chemotherapy has
substantial side effects and leads easily to cancer treatment failure. Therefore, exploring and …

Recent advances on modulation of H2O2 in tumor microenvironment for enhanced cancer therapeutic efficacy

Z Chu, J Yang, W Zheng, J Sun, W Wang… - Coordination Chemistry …, 2023 - Elsevier
Due to the rapid proliferation of tumors, the hydrogen peroxide (H 2 O 2) concentration of
tumor cells is higher than that of normal cells, which can be used as an effective target for …

Design of a two-dimensional interplanar heterojunction for catalytic cancer therapy

Y Kang, Z Mao, Y Wang, C Pan, M Ou, H Zhang… - Nature …, 2022 - nature.com
Limited substrates content is a major hurdle dampening the antitumor effect of catalytic
therapy. Herein, a two-dimensional interplanar heterojunction (FeOCl/FeOOH NSs) with· OH …

Synthesis of Copper Peroxide Nanodots for H2O2 Self-Supplying Chemodynamic Therapy

LS Lin, T Huang, J Song, XY Ou, Z Wang… - Journal of the …, 2019 - ACS Publications
Chemodynamic therapy (CDT) employs Fenton catalysts to kill cancer cells by converting
intracellular H2O2 into hydroxyl radical (• OH), but endogenous H2O2 is insufficient to …