Myocarditis can result from various infectious and non‐infectious causes that can lead to
dilated cardiomyopathy (DCM) and heart failure. Among the infectious causes, viruses are …

The risk determinants of type 1 diabetes, initiators of autoimmune response, mechanisms
regulating progress toward β cell failure, and factors determining time of presentation of …

In the present article, we propose the perspective that abnormal glutamate homeostasis
might contribute to diabetes pathogenesis. Previous reports and our recent data indicate that …

Homologues of signal peptide peptidase (SPPLs) are putative aspartic proteases that may
catalyse regulated intramembrane proteolysis of type II membrane-anchored signalling …

Although B cells play a pathogenic role in the initiation of type 1 diabetes (T1D) in NOD
mice, it is not known whether activated B cells can maintain tolerance and transfer protection …

Abstract Islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP) is
recognized as a major autoantigen for autoimmune type 1 diabetes (T1D) in the NOD mouse …

Introduction: Cell therapy can overcome the limitation of conventional treatments (including
different medications and β cell replacement) for type 1 diabetes. Based-on several studies …

On fractionation the ethanolic extract of H. rosa sinensis leaves, 5 fractions were obtained.
Of these, fraction-3 (F3) and fraction-5 (F5) were chosen for detailed investigation on non …

Regulatory T-cells (Treg) have a crucial role in limiting physiologic autoreactivity. Foxp3 is a
master regulator transcription factor of Treg differentiation and active Treg cells express high …

The DRB1* 15: 01-DQB1* 06: 02 (DR1501-DQ6) haplotype is linked to dominant protection
from type 1 diabetes, but the cellular mechanism for this association is unclear. To address …