Signal transducer and activator of transcription‐3, inflammation, and cancer: how intimate is the relationship?

BB Aggarwal, AB Kunnumakkara… - Annals of the New …, 2009 - Wiley Online Library
Signal transducer and activator of transcription‐3 (STAT‐3) is one of six members of a family
of transcription factors. It was discovered almost 15 years ago as an acute‐phase response …

Three-dimensional printing of Hela cells for cervical tumor model in vitro

Y Zhao, R Yao, L Ouyang, H Ding, T Zhang… - …, 2014 - iopscience.iop.org
Advances in three-dimensional (3D) printing have enabled the direct assembly of cells and
extracellular matrix materials to form in vitro cellular models for 3D biology, the study of …

An amino-bisphosphonate targets MMP-9–expressing macrophages and angiogenesis to impair cervical carcinogenesis

E Giraudo, M Inoue, D Hanahan - The Journal of clinical …, 2004 - Am Soc Clin Investig
A mouse model involving the human papillomavirus type-16 oncogenes develops cervical
cancers by lesional stages analogous to those in humans. In this study the angiogenic …

Tumoral and stromal expression of MMP-2, MMP-9, MMP-14, TIMP-1, TIMP-2, and VEGF-A in cervical cancer patient survival: a competing risk analysis

JM Azevedo Martins, SH Rabelo-Santos… - Bmc Cancer, 2020 - Springer
Background Expression of matrix metalloproteases 2, 9 and 14 (MMP-2, MMP-9, MMP-14),
tissue inhibitors of metalloprotease 1 and 2 (TIMP-1, TIMP-2) and vascular endothelial …

Histone deacetylase (HDAC) 10 suppresses cervical cancer metastasis through inhibition of matrix metalloproteinase (MMP) 2 and 9 expression

C Song, S Zhu, C Wu, J Kang - Journal of Biological Chemistry, 2013 - ASBMB
Aberrant expression of histone deacetylases (HDACs) is associated with carcinogenesis.
Some HDAC inhibitors are widely considered as promising anticancer therapeutics. A major …

In vitro modulation of MMP-2 and MMP-9 in human cervical and ovarian cancer cell lines by cytokines, inducers and inhibitors

MW Roomi, JC Monterrey, T Kalinovsky… - Oncology …, 2010 - spandidos-publications.com
Matrix metalloproteinases (MMPs) secreted by cervical and ovarian cancer, especially MMP-
2 and MMP-9, play crucial roles in tumor invasion and metastasis. We examined the effect of …

Tumor–stromal cell contact promotes invasion of human uterine cervical carcinoma cells by augmenting the expression and activation of stromal matrix …

T Sato, T Sakai, Y Noguchi, M Takita, S Hirakawa… - Gynecologic …, 2004 - Elsevier
Objective. The augmentation of the expression and activation of matrix metalloproteinases
(MMPs) is associated with tumor invasion and metastasis. In addition, tumor–stromal cell …

The impact of human papilloma viruses, matrix metallo-proteinases and HIV protease inhibitors on the onset and progression of uterine cervix epithelial tumors: a …

G Barillari, P Monini, C Sgadari, B Ensoli - International Journal of …, 2018 - mdpi.com
Infection of uterine cervix epithelial cells by the Human Papilloma Viruses (HPV) is
associated with the development of dysplastic/hyperplastic lesions, termed cervical …

Expression of membrane type 1 matrix metalloproteinase is associated with cervical carcinoma progression and invasion

Y Zhai, KB Hotary, B Nan, FX Bosch, N Muñoz… - Cancer research, 2005 - AACR
Membrane type 1 matrix metalloproteinase (MT1-MMP) is frequently expressed by cancer
cells and is believed to play an important role in cancer cell invasion and metastasis …

Kaempferia parviflora Extract Exhibits Anti-cancer Activity against HeLa Cervical Cancer Cells

S Potikanond, S Sookkhee, M Na Takuathung… - Frontiers in …, 2017 - frontiersin.org
Kaempferia parviflora (KP) has been traditionally used as a folk remedy to treat several
diseases including cancer, and several studies have reported cytotoxic activities of extracts …