Achalasia is a rare disorder of the oesophageal smooth muscle characterized by impaired
relaxation of the lower oesophageal sphincter (LES) and absent or spastic contractions in …

Dysphagia is a symptom of swallowing dysfunction that occurs between the mouth and the
stomach. Although oropharyngeal dysphagia is a highly prevalent condition (occurring in up …

Background Pneumatic dilation and laparoscopic Heller's myotomy (LHM) are established
treatments for idiopathic achalasia. Peroral endoscopic myotomy (POEM) is a less invasive …

Achalasia is a relatively rare primary motor esophageal disorder, characterized by absence
of relaxations of the lower esophageal sphincter and of peristalsis along the esophageal …

Objective Achalasia is a chronic motility disorder of the oesophagus for which laparoscopic
Heller myotomy (LHM) and endoscopic pneumodilation (PD) are the most commonly used …

Introduction Achalasia is a primary motor disorder of the oesophagus characterised by
absence of peristalsis and insufficient lower oesophageal sphincter relaxation. With new …

Background The recently developed technique for peroral endoscopic myotomy (POEM) has
been shown to be effective in several short-term studies. Longer term outcome data are …

Background The introduction of high-resolution manometry and the Chicago classification
has made it possible to diagnose achalasia and predict treatment response accurately. The …

Peroral endoscopic myotomy (POEM) is a novel clinical technique developed in Japan used
to treat esophageal achalasia and esophageal motility disorders. This technique has been …

Background 2-year follow-up data from our randomised controlled trial showed that peroral
endoscopic myotomy is associated with a significantly higher efficacy than pneumatic …