Animal models of major depression and their clinical implications
Major depressive disorder is a common, complex, and potentially life-threatening mental
disorder that imposes a severe social and economic burden worldwide. Over the years …
disorder that imposes a severe social and economic burden worldwide. Over the years …
Airborne particulate matter: human exposure and health effects
JE Thompson - Journal of occupational and environmental …, 2018 - journals.lww.com
Objective: Exposure to airborne particulate matter (PM) is estimated to cause millions of
premature deaths annually. This work conveys known routes of exposure to PM and …
premature deaths annually. This work conveys known routes of exposure to PM and …
Obesity-induced cellular senescence drives anxiety and impairs neurogenesis
Cellular senescence entails a stable cell-cycle arrest and a pro-inflammatory secretory
phenotype, which contributes to aging and age-related diseases. Obesity is associated with …
phenotype, which contributes to aging and age-related diseases. Obesity is associated with …
Parental olfactory experience influences behavior and neural structure in subsequent generations
BG Dias, KJ Ressler - Nature neuroscience, 2014 - nature.com
Using olfactory molecular specificity, we examined the inheritance of parental traumatic
exposure, a phenomenon that has been frequently observed, but not understood. We …
exposure, a phenomenon that has been frequently observed, but not understood. We …
Olfactory inputs modulate respiration-related rhythmic activity in the prefrontal cortex and freezing behavior
Respiration and airflow through the nasal cavity are known to be correlated with rhythmic
neural activity in the central nervous system. Here we show in rodents that during …
neural activity in the central nervous system. Here we show in rodents that during …
Olfactory impairment in psychiatric disorders: Does nasal inflammation impact disease psychophysiology?
Y Hasegawa, M Ma, A Sawa, AP Lane… - Translational …, 2022 - nature.com
Olfactory impairments contribute to the psychopathology of mental illnesses such as
schizophrenia and depression. Recent neuroscience research has shed light on the …
schizophrenia and depression. Recent neuroscience research has shed light on the …
Anxiety-and depression-like states lead to pronounced olfactory deficits and impaired adult neurogenesis in mice
E Siopi, M Denizet, MM Gabellec… - Journal of …, 2016 - Soc Neuroscience
Numerous clinical reports underscore the frequency of olfactory impairments in patients
suffering from major depressive disorders (MDDs), yet the underlying physiopathological …
suffering from major depressive disorders (MDDs), yet the underlying physiopathological …
Ablation of type III adenylyl cyclase in mice causes reduced neuronal activity, altered sleep pattern, and depression-like phenotypes
X Chen, J Luo, Y Leng, Y Yang, LS Zweifel… - Biological …, 2016 - Elsevier
Background Although major depressive disorder (MDD) has low heritability, a genome-wide
association study in humans has recently implicated type 3 adenylyl cyclase (AC3; ADCY3) …
association study in humans has recently implicated type 3 adenylyl cyclase (AC3; ADCY3) …
Disruptive physiology: olfaction and the microbiome–gut–brain axis
J Bienenstock, WA Kunze, P Forsythe - Biological Reviews, 2018 - Wiley Online Library
This review covers the field of olfaction and chemosensation of odorants and puts this
information into the context of interactions between microbes and behaviour; the microbiome …
information into the context of interactions between microbes and behaviour; the microbiome …
Perception and emotions: on the relationships between stress and olfaction
V Bombail - Applied animal behaviour science, 2019 - Elsevier
Adaptations to the ever changing social and physical environment are necessary,
sometimes involving the stress response. Olfaction is a chemical sense allowing the …
sometimes involving the stress response. Olfaction is a chemical sense allowing the …