Animal models of major depression and their clinical implications

B Czéh, E Fuchs, O Wiborg, M Simon - Progress in neuro …, 2016 - Elsevier
Major depressive disorder is a common, complex, and potentially life-threatening mental
disorder that imposes a severe social and economic burden worldwide. Over the years …

Airborne particulate matter: human exposure and health effects

JE Thompson - Journal of occupational and environmental …, 2018 - journals.lww.com
Objective: Exposure to airborne particulate matter (PM) is estimated to cause millions of
premature deaths annually. This work conveys known routes of exposure to PM and …

Obesity-induced cellular senescence drives anxiety and impairs neurogenesis

M Ogrodnik, YI Zhu, LGP Langhi, T Tchkonia, P Krüger… - Cell metabolism, 2019 - cell.com
Cellular senescence entails a stable cell-cycle arrest and a pro-inflammatory secretory
phenotype, which contributes to aging and age-related diseases. Obesity is associated with …

Parental olfactory experience influences behavior and neural structure in subsequent generations

BG Dias, KJ Ressler - Nature neuroscience, 2014 - nature.com
Using olfactory molecular specificity, we examined the inheritance of parental traumatic
exposure, a phenomenon that has been frequently observed, but not understood. We …

Olfactory inputs modulate respiration-related rhythmic activity in the prefrontal cortex and freezing behavior

AH Moberly, M Schreck, JP Bhattarai, LS Zweifel… - Nature …, 2018 - nature.com
Respiration and airflow through the nasal cavity are known to be correlated with rhythmic
neural activity in the central nervous system. Here we show in rodents that during …

Olfactory impairment in psychiatric disorders: Does nasal inflammation impact disease psychophysiology?

Y Hasegawa, M Ma, A Sawa, AP Lane… - Translational …, 2022 - nature.com
Olfactory impairments contribute to the psychopathology of mental illnesses such as
schizophrenia and depression. Recent neuroscience research has shed light on the …

Anxiety-and depression-like states lead to pronounced olfactory deficits and impaired adult neurogenesis in mice

E Siopi, M Denizet, MM Gabellec… - Journal of …, 2016 - Soc Neuroscience
Numerous clinical reports underscore the frequency of olfactory impairments in patients
suffering from major depressive disorders (MDDs), yet the underlying physiopathological …

Ablation of type III adenylyl cyclase in mice causes reduced neuronal activity, altered sleep pattern, and depression-like phenotypes

X Chen, J Luo, Y Leng, Y Yang, LS Zweifel… - Biological …, 2016 - Elsevier
Background Although major depressive disorder (MDD) has low heritability, a genome-wide
association study in humans has recently implicated type 3 adenylyl cyclase (AC3; ADCY3) …

Disruptive physiology: olfaction and the microbiome–gut–brain axis

J Bienenstock, WA Kunze, P Forsythe - Biological Reviews, 2018 - Wiley Online Library
This review covers the field of olfaction and chemosensation of odorants and puts this
information into the context of interactions between microbes and behaviour; the microbiome …

Perception and emotions: on the relationships between stress and olfaction

V Bombail - Applied animal behaviour science, 2019 - Elsevier
Adaptations to the ever changing social and physical environment are necessary,
sometimes involving the stress response. Olfaction is a chemical sense allowing the …