Cerebral malaria (CM), results from Plasmodium falciparum infection, and has a high
mortality rate. CM survivors can retain life-long post CM sequelae, including seizures and …

Abstract Neuregulin-1 (Nrg-1) is a member of the Neuregulin family of growth factors with
essential roles in the developing and adult nervous system. Six different types of Nrg-1 (Nrg …

Cerebral malaria is a life-threatening complication of malaria caused by the parasite
Plasmodium falciparum. The growing problem of drug resistance and the dearth of new …

Cerebral malaria (CM) caused by Plasmodium falciparum is a fatal neurological
complication of malaria, resulting in coma and death, and even survivors may suffer long …

Background We previously demonstrated that neuregulin-1 (NRG-1) was neuroprotective in
rats following ischemic stroke. Neuroprotection by NRG-1 was associated with the …

Reorganization of host red blood cells by the malaria parasite Plasmodium falciparum
enables their sequestration via attachment to the microvasculature. This artificially increases …

Cerebral malaria is a severe neuropathological complication of Plasmodium falciparum
infection. It results in high mortality and post-recovery neuro-cognitive disorders in children …

Human cerebral malaria (HCM), a severe encephalopathy associated with Plasmodium
falciparum infection, has a 20–30% mortality rate and predominantly affects African children …

Abstract Background Neuregulin-1 (NRG-1) has been shown to act as a neuroprotectant in
animal models of nerve agent intoxication and other acute brain injuries. We recently …

Background Human cerebral malaria (HCM) is a severe form of malaria characterized by
sequestration of infected erythrocytes (IRBCs) in brain microvessels, increased levels of …