Guanine-rich DNA sequences can fold into four-stranded, noncanonical secondary
structures called G-quadruplexes (G4s). G4s were initially considered a structural curiosity …

Abstract G-quadruplex (G4) DNA is a type of quadruple helix structure formed by a
continuous guanine-rich DNA sequence. Emerging evidence in recent years authenticated …

Abstract Guanine-quadruplexes (G4s) are non-canonical four-stranded structures that can
be formed in guanine (G) rich nucleic acid sequences. A great number of G-rich sequences …

The secondary structures of nucleic acids have an important influence on their cellular
functions but can be difficult to identify and classify quickly. Here, we show that an arrayed …

G-quadruplex is a three-dimensional secondary structure of nucleic acids formed by the
Hoogsteen hydrogen pairing of four guanines. Diverse topologies of G-quadruplex could be …

Abstract G-Quadruplexes (G4s) are widely studied secondary DNA/RNA structures, naturally
occurring when G-rich sequences are present. The strategic localization of G4s in genome …

We report on higher-order G-quadruplex structures adopted by long promoter sequences
obtained by an iterative integrated structural biology approach. Our approach uses …

G-quadruplex (G4) binding proteins regulate important biological processes, but their
interaction networks are poorly understood. We report the first use of G4 as a warhead of a …

Introduction Guanine-rich DNA sequences can fold into four-stranded noncanonical
secondary structures called G-quadruplexes (G4s) which are widely distributed in functional …

A G-rich sequence was designed to allow folding into either a stable parallel or hybrid-type
topology. With the parent sequence featuring coexisting species, various related sequences …