Purines perform many important functions in the cell, being the formation of the monomeric
precursors of nucleic acids DNA and RNA the most relevant one. Purines which also …

Adenosine monophosphate‐activated protein kinase (AMPK) senses metabolic stress and
integrates diverse physiological signals to restore energy balance. Multiple functions are …

Background Autism is a complex neurodevelopmental disorder that usually presents in early
childhood and that is thought to be influenced by genetic and environmental factors …

The growing evidence of the involvement of purine compounds in signaling, of nucleotide
imbalance in tumorigenesis, the discovery of purinosome and its regulation, cast new light …

Acadesine, 5-aminoimidazole-4-carboxamide (AICA) riboside, induced apoptosis in B-cell
chronic lymphocytic leukemia (B-CLL) cells in all samples tested (n= 70). The half-maximal …

Adenosine, acting both through G-protein coupled adenosine receptors and intracellularly,
plays a complex role in multiple physiological and pathophysiological processes by …

Purines and pyrimidines, regarded for a long time only as building blocks for nucleic acid
synthesis and intermediates in the transfer of metabolic energy, gained increasing attention …

5′-Aminoimidazole-4-carboxamide riboside (AICA riboside) has been previously shown to
be toxic to two neuronal cell models [Neuroreport 11 (2000) 1827]. In this paper we …

Media used for equine sperm storage often contain relatively high concentrations of glucose,
even though stallion spermatozoa preferentially utilize oxidative phosphorylation (OXPHOS) …

Adenosine is a product of complete dephosphorylation of adenine nucleotides which takes
place in various compartments of the cell. This nucleoside is a significant signal molecule …