Gradients and consequences of heterogeneity in biofilms

J Jo, A Price-Whelan, LEP Dietrich - Nature Reviews Microbiology, 2022 - nature.com
Historically, appreciation for the roles of resource gradients in biology has fluctuated
inversely to the popularity of genetic mechanisms. Nevertheless, in microbiology specifically …

Biofilms: architecture, resistance, quorum sensing and control mechanisms

P Saxena, Y Joshi, K Rawat, R Bisht - Indian journal of microbiology, 2019 - Springer
Biofilm is a mode of living employed by many pathogenic and environmental microbes to
proliferate as multicellular aggregates on inert inanimate or biological substrates. Several …

Interkingdom assemblages in human saliva display group-level surface mobility and disease-promoting emergent functions

Z Ren, H Jeckel, A Simon-Soro… - Proceedings of the …, 2022 - National Acad Sciences
Fungi and bacteria often engage in complex interactions, such as the formation of
multicellular biofilms within the human body. Knowledge about how interkingdom biofilms …

Topical ferumoxytol nanoparticles disrupt biofilms and prevent tooth decay in vivo via intrinsic catalytic activity

Y Liu, PC Naha, G Hwang, D Kim, Y Huang… - Nature …, 2018 - nature.com
Ferumoxytol is a nanoparticle formulation approved by the US Food and Drug
Administration for systemic use to treat iron deficiency. Here, we show that, in addition …

[HTML][HTML] Precision targeting of bacterial pathogen via bi-functional nanozyme activated by biofilm microenvironment

Y Huang, Y Liu, S Shah, D Kim, A Simon-Soro, T Ito… - Biomaterials, 2021 - Elsevier
Human dental caries is an intractable biofilm-associated disease caused by microbial
interactions and dietary sugars on the host's teeth. Commensal bacteria help control …

The role of biofilm in the development and dissemination of ubiquitous pathogens in drinking water distribution systems: an overview of surveillance, outbreaks, and …

BA Hemdan, GE El-Taweel, P Goswami, D Pant… - World Journal of …, 2021 - Springer
A variety of pathogenic microorganisms can survive in the drinking water distribution
systems (DWDS) by forming stable biofilms and, thus, continually disseminating their …

pH-dependent delivery of chlorhexidine from PGA grafted mesoporous silica nanoparticles at resin-dentin interface

Z Akram, S Aati, H Ngo, A Fawzy - Journal of Nanobiotechnology, 2021 - Springer
Background A low pH environment is created due to the production of acids by oral biofilms
that further leads to the dissolution of hydroxyapatite crystal in the tooth structure significantly …

Intra-colony channels in E. coli function as a nutrient uptake system

LM Rooney, WB Amos, PA Hoskisson… - The ISME …, 2020 - academic.oup.com
The ability of microorganisms to grow as aggregated assemblages has been known for
many years, however their structure has remained largely unexplored across multiple spatial …

Redox/pH dual-controlled release of chlorhexidine and silver ions from biodegradable mesoporous silica nanoparticles against oral biofilms

M Lu, Y Ge, J Qiu, D Shao, Y Zhang, J Bai… - International journal …, 2018 - Taylor & Francis
Background Oral plaque biofilms pose a threat to periodontal health and are challenging to
eradicate. There is a growing belief that a combination of silver nanoparticles and …

Synchrotron X-ray studies of the structural and functional hierarchies in mineralised human dental enamel: A state-of-the-art review

C Besnard, A Marie, S Sasidharan, RA Harper… - Dentistry Journal, 2023 - mdpi.com
Hard dental tissues possess a complex hierarchical structure that is particularly evident in
enamel, the most mineralised substance in the human body. Its complex and interlinked …