Since its discovery in 2006 by Oh-I and colleagues, NUCB2/nesfatin-1 encoded by
nucleobindin-2 (NUCB2) has drawn sustained attention as reflected in over 500 …

Nesfatin-1 was discovered as an anorexigenic peptide derived from proteolytic cleavage of
the prepropeptide, nucleobindin 2 (NUCB2). It is widely expressed in central as well as …

Aims To evaluate the correlation of nesfatin-1, GSH and SOD levels with β-cell insulin
secretion and their influence on insulin secretion in the development of type 2 diabetes …

Nesfatin-1, derived from the nucleobindin 2 (NUCB2) precursor, is a potent anorexigenic
peptide that was discovered in 2006. Since its identification in the hypothalamus, it has been …

Abstract NUCB2/nesfatin-1 is an anorexigenic peptide hormone first known for its effects on
energy homeostasis. More recently, a growing evidence suggests a role of NUCB2/nesfatin …

Nesfatin-1, deriving from a precursor protein, NUCB2, is a newly discovered molecule with
anti-apoptotic, anti-inflammatory, antioxidant, and anorexigenic effects. It was initially …

Background Previous studies have investigated the relationship between nesfatin-1 level
and polycystic ovary syndrome (PCOS). However, these studies have produced conflicting …

Methods Sprague-Dawley rats were fed with normal diet (ND) or HFD. Gastric emptying rate
was measured following NES-1 (5 pmol/rat, intracerebroventricular) preceded by …

The regulation of food intake encompasses complex interplays between the gut and the
brain. Among them, the gastrointestinal tract releases different peptides that communicate …

Background Nesfatin-1 has been described as an anorexigenic peptide. Comprehensive
evidence also points towards an involvement of nesfatin-1 in the modulation of emotional …