Immunotherapy has made significant strides in cancer treatment, particularly through
immune checkpoint blockade (ICB), which has shown notable clinical benefits across …

Migraine is a complex neurological disorder and a major cause of disability. A wide range of
different drug classes such as triptans, antidepressants, anticonvulsants, analgesics, and …

The effects of environmental factors and epigenetics on health and disease development
are complex and interconnected. Environmental factors encompass external influences like …

Brain tumours are the leading cause of paediatric cancer-associated death worldwide. High-
grade glioma (HGG) represents a main cause of paediatric brain tumours and is associated …

Cataract, a disease that causes opacity of the lens, is the leading cause of blindness
worldwide. Cataracts secondary to diabetes are common, even in young patients, so they …

Head and Neck Squamous Cell Carcinoma (HNSCC) is a highly heterogeneous group of
tumors characterized by an incidence of 650,000 new cases and 350,000 deaths per year …

Epigenetics mainly refers to covalent modifications to DNA or histones without affecting
genomes, which ultimately lead to phenotypic changes in cells or organisms. Given the …

Background The incidence of non-alcoholic fatty liver disease (NAFLD)-associated
hepatocellular carcinoma (HCC) is increasing worldwide, but the steps in precancerous …

Cancer is a highly heterogeneous disease that poses a serious threat to human health
worldwide. Despite significant advances in the diagnosis and treatment of cancer, the …

In dogs, mammary cancer is the most common tumor type, especially in unspayed females.
As in humans, this type of cancer has spontaneous development and is influenced by …