Depression, anxiety, and apathy in mild cognitive impairment: current perspectives

L Ma - Frontiers in aging neuroscience, 2020 - frontiersin.org
Objective: Mild cognitive impairment (MCI) is an important risk state for dementia, particularly
Alzheimer's disease (AD). Depression, anxiety, and apathy are commonly observed …

Depression, dementia and immune dysregulation

S Hayley, AM Hakim, PR Albert - Brain, 2021 - academic.oup.com
Major depression is a prevalent illness that increases the risk of several neurological
conditions. These include stroke, cardiovascular disease, and dementia including …

Depression and suicide risk screening: updated evidence report and systematic review for the US preventive services task force

EA O'Connor, LA Perdue, EL Coppola, ML Henninger… - JAMA, 2023 - jamanetwork.com
Importance Depression is common and associated with substantial burden. Suicide rates
have increased over the past decade, and both suicide attempts and deaths have …

Depression in Alzheimer's disease: epidemiology, mechanisms, and treatment

YY Huang, YH Gan, L Yang, W Cheng, JT Yu - Biological Psychiatry, 2024 - Elsevier
Depression and Alzheimer's disease (AD) are substantial public health concerns. In the past
decades, a link between the 2 disease entities has received extensive acknowledgment, yet …

[HTML][HTML] Cognitive impairment and depression: meta-analysis of structural magnetic resonance imaging studies

L Zackova, M Jani, M Brazdil, YS Nikolova… - NeuroImage: Clinical, 2021 - Elsevier
Longitudinal comorbidity of depression and cognitive impairment has been reported by
number of epidemiological studies but the underlying mechanisms explaining the link …

Universal depression prevention: An umbrella review of meta-analyses

E Hoare, S Collins, W Marx, E Callaly… - Journal of psychiatric …, 2021 - Elsevier
Depression is a disabling, highly prevalent, frequently chronic, and difficult-to-treat disorder
with an immense cognitive, social, and economic burden. Given that many of the advances …

Neuropsychiatric symptoms in cognitively normal older persons, and the association with Alzheimer's and non-Alzheimer's dementia

TM Liew - Alzheimer's Research & Therapy, 2020 - Springer
Background Neuropsychiatric symptoms (NPS) have been reported to be useful in
predicting incident dementia among cognitively normal older persons. However, the …

Gut microbiome predicts cognitive function and depressive symptoms in late life

A Kolobaric, C Andreescu, E Jašarević, CH Hong… - Molecular …, 2024 - nature.com
Depression in older adults with cognitive impairment increases progression to dementia.
Microbiota is associated with current mood and cognition, but the extent to which it predicts …

Neuropsychiatric symptoms in mild cognitive impairment and dementia due to AD: relation with disease stage and cognitive deficits

WA Wiels, MMJ Wittens, D Zeeuws, C Baeken… - Frontiers in …, 2021 - frontiersin.org
Background: The interaction between neuropsychiatric symptoms, mild cognitive impairment
(MCI), and dementia is complex and remains to be elucidated. An additive or multiplicative …

Effect of vortioxetine on cognitive impairment in patients with major depressive disorder: a systematic review and meta-analysis of randomized controlled trials

IC Huang, TS Chang, C Chen… - International Journal of …, 2022 - academic.oup.com
Background Dementia and depression are increasingly common worldwide, and their
effective control could ease the burden on economies, public health systems, and support …