[HTML][HTML] The multifaceted role of SNARE proteins in membrane fusion

J Han, K Pluhackova, RA Böckmann - Frontiers in physiology, 2017 - frontiersin.org
Membrane fusion is a key process in all living organisms that contributes to a variety of
biological processes including viral infection, cell fertilization, as well as intracellular …

[HTML][HTML] Novel cellular functions of very long chain-fatty acids: insight from ELOVL4 mutations

F Deák, RE Anderson, JL Fessler… - Frontiers in cellular …, 2019 - frontiersin.org
Elongation of Very Long chain fatty acids-4 (ELOVL4) protein is a member of the ELOVL
family of fatty acid elongases that is collectively responsible for catalyzing formation of long …

[HTML][HTML] Munc18 and Munc13 serve as a functional template to orchestrate neuronal SNARE complex assembly

S Wang, Y Li, J Gong, S Ye, X Yang, R Zhang… - Nature …, 2019 - nature.com
The transition of the Munc18-1/syntaxin-1 complex to the SNARE complex, a key step
involved in exocytosis, is regulated by Munc13-1, SNAP-25 and synaptobrevin-2, but the …

[HTML][HTML] Lipid and lipidation in membrane fusion

A Sardar, N Dewangan, B Panda, D Bhowmick… - The Journal of …, 2022 - Springer
Membrane fusion plays a lead role in the transport of vesicles, neurotransmission,
mitochondrial dynamics, and viral infection. There are fusion proteins that catalyze and …

Neuronal SNARE complex assembly guided by Munc18‐1 and Munc13‐1

S Wang, C Ma - FEBS Open Bio, 2022 - Wiley Online Library
Neurotransmitter release by Ca2+‐triggered synaptic vesicle exocytosis is essential for
information transmission in the nervous system. The soluble N‐ethylmaleimide sensitive …

[HTML][HTML] SNARE modulators and SNARE mimetic peptides

M Khvotchev, M Soloviev - Biomolecules, 2022 - mdpi.com
The soluble N-ethylmaleimide-sensitive factor (NSF) attachment protein (SNAP) receptor
(SNARE) proteins play a central role in most forms of intracellular membrane trafficking, a …

[HTML][HTML] v-SNARE transmembrane domains function as catalysts for vesicle fusion

M Dhara, A Yarzagaray, M Makke, B Schindeldecker… - Elife, 2016 - elifesciences.org
Vesicle fusion is mediated by an assembly of SNARE proteins between opposing
membranes, but it is unknown whether transmembrane domains (TMDs) of SNARE proteins …

[HTML][HTML] Intracellular vesicle fusion requires a membrane-destabilizing peptide located at the juxtamembrane region of the v-SNARE

SS Rathore, Y Liu, H Yu, C Wan, MS Lee, Q Yin… - Cell reports, 2019 - cell.com
Intracellular vesicle fusion is mediated by soluble N-ethylmaleimide sensitive factor
attachment protein receptors (SNAREs) and Sec1/Munc18 (SM) proteins. It is generally …

[HTML][HTML] Structural insights into membrane fusion mediated by convergent small fusogens

Y Yang, NN Margam - Cells, 2021 - mdpi.com
From lifeless viral particles to complex multicellular organisms, membrane fusion is
inarguably the important fundamental biological phenomena. Sitting at the heart of …

[HTML][HTML] Fusion peptide induced modification of membrane organization and dynamics: Implications in developing fusion inhibitors

S Mishra, MS Panda, H Chakraborty - Chemical Physics Impact, 2023 - Elsevier
An essential step in the entrance of enveloped viruses such as coronaviruses, the human
immunodeficiency virus, and influenza is membrane fusion. A unique class of glycoprotein …