Lipids have essential biological functions in the body (eg, providing energy storage, acting
as a signaling molecule, and being a structural component of membranes); however, an …

Diet, serving as a vital source of nutrients, exerts a profound influence on human health and
disease progression. Recently, dietary interventions have emerged as promising adjunctive …

Low-grade glioma (LGG) is a grade II-III glioma accompanied by distinct clinical and
molecular characteristics and the studies related to its prognosis are still unclear. The …

Oral cancer is one of the leading causes of death worldwide, with a reported 5-year survival
rate of around 50% after treatment. Epigenetic modifications are considered to have a key …

Obesity is associated with an increased risk for 13 different cancers. The increased risk for
cancer in obesity is mediated by obesity-associated changes in the immune system. Obesity …

Metabolic reprogramming has been considered a core hallmark of cancer, in which
excessive accumulation of lipids promote cancer initiation, progression and metastasis …

Obesity is a chronic disease caused by the accumulation of excessive adipose tissue. This
disorder is characterized by chronic low‑grade inflammation, which promotes the release of …

Proprotein convertase subtilisin/kexin type 9 (PCSK9) has been demonstrated to play a
critical role in regulating cholesterol homeostasis and T cell antitumor immunity. However …

Oral squamous cell carcinoma (OSCC) accounts for around 90% of all oral cancers and is
the eighth most common cancer worldwide. Despite progress in managing OSCC, the …

During tumor initiation and progression, the complicated role of immune cells in the tumor
immune microenvironment remains a concern. Myeloid-derived suppressor cells (MDSCs) …