Engineered extracellular vesicles for cancer therapy
X Zhang, H Zhang, J Gu, J Zhang, H Shi… - Advanced …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) have emerged as a novel cell‐free strategy for the treatment of
many diseases including cancer. As a result of their natural properties to mediate cell‐to‐cell …
many diseases including cancer. As a result of their natural properties to mediate cell‐to‐cell …
The challenge and prospect of mRNA therapeutics landscape
Messenger RNA (mRNA)-based therapeutics hold the potential to cause a major revolution
in the pharmaceutical industry because they can be used for precise and individualized …
in the pharmaceutical industry because they can be used for precise and individualized …
Through scalp and skull NIR‐II photothermal therapy of deep orthotopic brain tumors with precise photoacoustic imaging guidance
Brain tumor is one of the most lethal cancers owing to the existence of blood–brain barrier
and blood–brain tumor barrier as well as the lack of highly effective brain tumor treatment …
and blood–brain tumor barrier as well as the lack of highly effective brain tumor treatment …
Extracellular vesicles as a drug delivery system: A systematic review of preclinical studies
During the past decades, extracellular vesicles (EVs) have emerged as an attractive drug
delivery system. Here, we assess their pre-clinical applications, in the form of a systematic …
delivery system. Here, we assess their pre-clinical applications, in the form of a systematic …
Exosomes in cancer nanomedicine and immunotherapy: prospects and challenges
Exosomes (versatile, cell-derived nanovesicles naturally endowed with exquisite target-
homing specificity and the ability to surmount in vivo biological barriers) hold substantial …
homing specificity and the ability to surmount in vivo biological barriers) hold substantial …
The application of exosomes and exosome-nanoparticle in treating brain disorders
Brain-derived exosomes (BDEs) are extracellular nanovesicles released by all central
nervous system cell lineages and contain cargo from the cells that produced them. In …
nervous system cell lineages and contain cargo from the cells that produced them. In …
The roles of small extracellular vesicles in cancer and immune regulation and translational potential in cancer therapy
Extracellular vesicles (EVs) facilitate the extracellular transfer of proteins, lipids, and nucleic
acids and mediate intercellular communication among multiple cells in the tumour …
acids and mediate intercellular communication among multiple cells in the tumour …
Extracellular vesicles: Emerging anti-cancer drugs and advanced functionalization platforms for cancer therapy
M Wu, M Wang, H Jia, P Wu - Drug Delivery, 2022 - Taylor & Francis
Increasing evidences show that unmodified extracellular vesicles (EVs) derived from various
cells can effectively inhibit the malignant progression of different types of tumors by …
cells can effectively inhibit the malignant progression of different types of tumors by …
Novel approaches in cancer treatment: preclinical and clinical development of small non-coding RNA therapeutics
R Cuciniello, S Filosa, S Crispi - Journal of Experimental & Clinical Cancer …, 2021 - Springer
Short or small interfering RNAs (siRNAs) and microRNA (miRNAs) are molecules similar in
size and function able to inhibit gene expression based on their complementarity with mRNA …
size and function able to inhibit gene expression based on their complementarity with mRNA …
Recent advances in the therapeutic strategies of glioblastoma multiforme
Glioblastoma multiforme (GBM) is one of the most common, most formidable, and deadliest
malignant types of primary astrocytoma with a poor prognosis. At present, the standard of …
malignant types of primary astrocytoma with a poor prognosis. At present, the standard of …