In mammals, the sperm activates the development of the egg by triggering a series of
oscillations in the cytosolic-free Ca 2+ concentration (Ca 2+ i). The sperm triggers these …

Inflammatory diseases attenuate reproductive functions in humans and domestic animals.
Lipopolysaccharide (LPS), an endotoxin released by bacteria, is known to disrupt female …

Insulin has long been recognized as a key regulator of energy homeostasis via its actions at
the level of the brain, but in addition, plays a role in regulating neural control of reproduction …

The molecular basis of ungulate and non-rodent conceptus elongation and gastrulation
remains poorly understood; however, use of state-of-the-art genomic technologies is …

Inflammation has a well-known suppressive effect on fertility. The function of gonadotropin-
releasing hormone (GnRH) neurons, the central regulator of fertility is substantially altered …

Endotoxemia can be caused by obesity, environmental chemical exposure, abiotic stressors
and bacterial infection. Circumstances that deleteriously impact intestinal barrier integrity …

The effect of stress on reproduction and gonadal function has captivated investigators for
almost 100 years. Following the identification of gonadotropin‐releasing hormone (GnRH) …

Ovulation is an essential phenomenon for reproduction in mammalian females along with
follicular growth. It is well established that gonadal function is controlled by the …

Introduction The impact of stress on reproductive function is significant. Hypothalamic
paraventricular nucleus (PVN) corticotrophin-releasing hormone (CRH) plays a major role in …

Background Immune stress induced by lipopolysaccharide (LPS) influences the
gonadotropin-releasing hormone (GnRH)/luteinizing hormone (LH) secretion. Presence of …